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Income Taxes - Additional Information (Detail) - USD ($) $ in Thousands | 12 Months Ended |
--- | --- | ---
Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019
Income Taxes [Line Items] |  |  |
Increase in valuation allowance due to net operating loss | $ 60,000 | $ 28,400 |
Unrecognized tax benefits | 21,944 | 8,677 | $ 3,558
Unrecognized tax benefits, if recognized would effective annual tax rate | 1,100 |  |
Accrued interest or penalties related to uncertain tax positions | 257 | $ 257 |
Domestic tax authority |  |  |
Income Taxes [Line Items] |  |  |
NOL carryforwards | 393,400 |  |
NOL carryforwards subject to expiration | 57,300 |  |
Domestic tax authority | Research Tax Credit Carryforward |  |  |
Income Taxes [Line Items] |  |  |
Tax credit carryforwards | 13,600 |  |
State credit carryforwards |  |  |
Income Taxes [Line Items] |  |  |
NOL carryforwards | 227,100 |  |
State credit carryforwards | Research Tax Credit Carryforward |  |  |
Income Taxes [Line Items] |  |  |
Tax credit carryforwards | 12,300 |  |
Foreign Tax Authority |  |  |
Income Taxes [Line Items] |  |  |
NOL carryforwards | $ 50,100 |  |

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- Definition Amount of operating loss carryforward, before tax effects, available to reduce future taxable income under enacted tax laws. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 3 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=121826272&loc=d3e32559-109319 + Details
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