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Income Taxes (Tables)
 12 Months Ended
Dec. 31, 2021
Income Tax Disclosure [Abstract]  
Schedule of Components of Loss Before Income Taxes The following table presents domestic and foreign components of loss before provision for income taxes:
Years ended December 31,
20212020
(In thousands)
U.S.$(145,375)$(110,327)
Foreign(165)(6,066)
Loss before income taxes$(145,540)$(116,393)
Schedule of Components of Income Tax Provision (Benefit) The components of the Company’s income tax provision (benefit) were as follows:
Years ended December 31,
20212020
(In thousands)
Current:
Foreign$— $1,114 
Total current tax provision— 1,114 
Deferred
Foreign— — 
Total deferred tax provision— — 
Total income tax provision$— $1,114 
Schedule of Reconciliation of Income Tax Expense Computed Statutory Federal Income Tax and Financial Statements Income tax provision for the years ended December 31, 2021 and 2020 differed from the amounts computed by applying the statutory federal income tax rate of 21% to pretax loss as a result of the following:
Years ended December 31,
20212020
(In thousands)
Federal income tax expense at statutory rate$(30,563)$(24,442)
Stock compensation1,662 (2,787)
Non-deductible expenses28 941 
Research and development tax credits(2,672)(3,150)
Change in valuation allowance41,324 24,817 
Foreign rate differential(9)595 
Impact of internal reorganization(9,763)2,669 
Uncertain tax positions— 2,305 
Other(7)166 
Total tax provision$— $1,114 
Schedule of Deferred Tax Assets The following table presents significant components of the Company’s deferred tax assets and liabilities:
As of December 31,
20212020
(In thousands)
Deferred tax assets:
Net operating loss carryforwards$111,741 $74,023 
Accruals, reserve and other2,255 1,588 
Tax credit carryforwards16,838 11,727 
Stock-based compensation9,741 5,975 
Intangibles1,613 18 
Lease obligation24,224 6,630 
Capital losses9,850 1 
Other17 1 
Total deferred tax assets before valuation allowance176,279 99,963 
Valuation allowance(154,672)(94,645)
Total deferred tax assets21,607 5,318 
Deferred tax liabilities:
Right-of-use assets(20,227)(4,183)
Property and equipment(1,380)(1,135)
Total deferred tax liabilities$(21,607)$(5,318)
Net deferred tax assets$— $— 
Schedule of Unrecognized Tax Benefits A reconciliation of the unrecognized tax benefits is as follows:
Years ended December 31,
20212020
(In thousands)
Unrecognized tax benefits as of the beginning of the year$8,677 $3,558 
Increase (decrease) related to prior year tax provisions10,656 — 
Increase related to current year tax provisions2,611 5,119 
Unrecognized tax benefits as of the end of the year$21,944 $8,677