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Income Taxes - Additional Information (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Income Taxes [Line Items]
Increase in valuation allowance due to net operating loss	$ 60,000	$ 28,400
Unrecognized tax benefits	21,944	8,677	$ 3,558
Unrecognized tax benefits, if recognized would effective annual tax rate	1,100
Accrued interest or penalties related to uncertain tax positions	257	$ 257
Domestic tax authority
Income Taxes [Line Items]
NOL carryforwards	393,400
NOL carryforwards subject to expiration	57,300
Domestic tax authority | Research Tax Credit Carryforward
Income Taxes [Line Items]
Tax credit carryforwards	13,600
State credit carryforwards
Income Taxes [Line Items]
NOL carryforwards	227,100
State credit carryforwards | Research Tax Credit Carryforward
Income Taxes [Line Items]
Tax credit carryforwards	12,300
Foreign Tax Authority
Income Taxes [Line Items]
NOL carryforwards	$ 50,100

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Income taxes.

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