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Equity Incentive Awards | 3 Months Ended
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Mar. 31, 2022
Share-based Payment Arrangement [Abstract] |
Equity Incentive Awards | Equity Incentive Awards Stock Options The following table summarizes the Company’s option activity and related information:
| Number of Options (in thousands) |  | Weighted- Average Exercise Price
Balance at December 31, 2021 | 13,288 |  |  | $ | 9.34 |
Options granted | 5,735 |  |  | 1.40 |
Options exercised | (15) |  |  | 0.19 |
Options forfeited | (2,837) |  |  | 6.60 |
Balance at March 31, 2022 | 16,171 |  |  | $ | 7.01 |
Exercisable as of March 31, 2022 | 3,921 |  |  | $ | 12.95 |
Options granted during the three months ended March 31, 2022 include 0.9 million shares of performance-based non-qualified options with both performance and service vesting conditions. Restricted Stock Units (“RSUs”) The following table summarizes the Company’s RSUs activity and related information:
| Number of Units (in thousands) |  | Weighted- Average Grant- Date Fair Value
Outstanding at December 31, 2021 | 2,126 |  |  | $ | 3.76 |
Granted | 858 |  |  | 1.43 |
Vested and released | (371) |  |  | 4.62 |
Forfeited | (91) |  |  | 3.83 |
Outstanding at March 31, 2022 | 2,522 |  |  | $ | 2.84 |
RSUs granted during the three months ended March 31, 2022 include 0.2 million shares of performance units with both performance and service vesting conditions. Stock-Based Compensation Expense The following table presents, by operating expense, the Company’s stock-based compensation expense:
| Three Months Ended March 31, |  |
| 2022 |  | 2021 |  |  |  |
| (In thousands)
Research and development | $ | 1,933 |  |  | $ | 2,339 |  |  |  |  |
General and administrative | 3,448 |  |  | 4,885 |  |  |  |  |
Total stock-based compensation expense | $ | 5,381 |  |  | $ | 7,224 |  |  |  |  |

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- Definition The entire disclosure for shareholders' equity and share-based payment arrangement. Includes, but is not limited to, disclosure of policy and terms of share-based payment arrangement, deferred compensation arrangement, and employee stock purchase plan (ESPP). + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -URI http://asc.fasb.org/topic&trid=2208762 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -URI http://asc.fasb.org/topic&trid=2228938 + Details
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