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v3.22.1

Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2022 | Mar. 31, 2021
Cash flows from operating activities: |  |
Net loss | $ (37,908) | $ (28,436)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 1,425 | 1,166
Stock-based compensation expense | 5,381 | 7,224
Amortization of premium and accrued interest on marketable securities | 212 | 855
Other | (92) | (42)
Changes in operating assets and liabilities: |  |
Prepaid expenses and other current assets | (2,916) | (1,279)
Other assets | (1,658) | (464)
Operating lease right-of-use asset | 1,126 | 332
Accounts payable | 1,437 | (763)
Accrued expenses and other current liabilities | (1,207) | (396)
Other non-current liabilities | 19 | 0
Lease liability and lease incentive receivable | 5,252 | (502)
Net cash used in operating activities | (28,929) | (22,305)
Cash flows from investing activities: |  |
Purchases of marketable securities | (29,750) | (82,667)
Maturities of marketable securities | 118,507 | 90,650
Purchases of property and equipment | (4,374) | (1,404)
Net cash provided by investing activities | 84,383 | 6,579
Cash flows from financing activities: |  |
Proceeds from offerings of common stock, net of issuance costs | 0 | 1,694
Proceeds from issuance of common stock pursuant to option exercises | 3 | 51
Repayment of loan | 0 | (240)
Net cash provided by financing activities | 3 | 1,505
Net increase (decrease) in cash and cash equivalents and restricted cash | 55,457 | (14,221)
Cash and cash equivalents and restricted cash at beginning of period | 36,698 | 63,423
Cash and cash equivalents and restricted cash at end of period | 92,155 | 49,202
Cash and cash equivalents | 89,652 | 45,422
Restricted cash | 2,503 | 3,780
Cash and cash equivalents and restricted cash at end of period | 92,155 | 49,202
Supplemental schedule of noncash investing and financing information |  |
Fixed assets in accounts payable, accrued expenses and other current liabilities | $ 2,616 | $ 805

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