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v3.22.2

Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2022 | Jun. 30, 2021
Cash flows from operating activities: |  |
Net loss | $ (81,669) | $ (72,769)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 3,028 | 2,361
Stock-based compensation expense | 10,323 | 15,458
Amortization of premium and accrued interest on marketable securities | 258 | 1,398
Loss on disposal of property and equipment | 101 | 0
Impairment of long-lived assets | 2,011 | 0
Other | (76) | (81)
Changes in operating assets and liabilities: |  |
Prepaid expenses and other current assets | (4,165) | (1,653)
Other assets | (3,403) | (99)
Operating lease right-of-use asset | 2,234 | 1,505
Accounts payable | 3,216 | (394)
Accrued expenses and other current liabilities | 2,172 | (583)
Other non-current liabilities | (38) | 0
Lease liability and lease incentive receivable | 8,200 | (1,363)
Net cash used in operating activities | (57,808) | (56,220)
Cash flows from investing activities: |  |
Purchases of marketable securities | (57,674) | (199,959)
Maturities of marketable securities | 183,599 | 240,377
Sales of marketable securities | 0 | 8,990
Purchases of property and equipment | (10,807) | (5,052)
Net cash provided by investing activities | 115,118 | 44,356
Cash flows from financing activities: |  |
Proceeds from offerings of common stock, net of issuance costs | 0 | 1,685
Proceeds from issuance of common stock pursuant to option exercises | 3 | 51
Proceeds from employee stock purchase plan | 362 | 526
Repayment of loan | 0 | (240)
Net cash provided by financing activities | 365 | 2,022
Net increase (decrease) in cash and cash equivalents and restricted cash | 57,675 | (9,842)
Cash and cash equivalents and restricted cash at beginning of period | 36,698 | 63,423
Cash and cash equivalents and restricted cash at end of period | 94,373 | 53,581
Cash and cash equivalents | 91,870 | 47,299
Restricted cash | 2,503 | 6,282
Cash and cash equivalents and restricted cash at end of period | 94,373 | 53,581
Supplemental schedule of noncash investing and financing information |  |
Right-of-use assets obtained in exchange for lease liability | 0 | 84,005
Fixed assets in accounts payable, accrued expenses and other current liabilities | $ 908 | $ 1,562

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