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Equity Incentive Awards (Tables)

6 Months Ended

Jun. 30, 2022

Share-Based Payment Arrangement [Abstract]

Summary of Stock Options Activity

The following table summarizes the Company’s option activity and related information:

			Number of Options (in thousands)						Weighted- Average Exercise Price
Balance at December 31, 2021			13,288						$	9.34
Options granted			6,994						1.33
Options exercised			(15)						0.19
Options forfeited			(3,469)						5.96
Balance at June 30, 2022			16,798						$	6.71
Exercisable as of June 30, 2022			4,739						$	12.02

Summary of Restricted Stock Units Activity

The following table summarizes the Company’s RSUs activity and related information:

			Number of Units (in thousands)						Weighted- Average Grant- Date Fair Value
Outstanding at December 31, 2021			2,126						$	3.76
Granted			857						1.43
Vested and released			(376)						4.64
Forfeited			(220)						2.51
Outstanding at June 30, 2022			2,387						$	2.90

Summary of Stock-Based Compensation Expense

The following table presents, by operating expense, the Company’s stock-based compensation expense:

			Three Months Ended June 30,												Six Months Ended June 30,
			2022						2021						2022						2021
			(In thousands)
Research and development			$	1,830					$	2,579					$	3,763					$	4,918
General and administrative			3,112						5,655						6,560						10,540
Total stock-based compensation expense			$	4,942					$	8,234					$	10,323					$	15,458

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Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement.

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
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Tabular disclosure of the number and weighted-average grant date fair value for restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock units that were granted, vested, or forfeited during the year.

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-Name Accounting Standards Codification
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Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

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