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Equity Incentive Awards (Tables)

9 Months Ended

Sep. 30, 2022

Share-Based Payment Arrangement [Abstract]

Schedule of Stock Options Activity

The following table summarizes the Company’s option activity and related information:

			Number of Options (in thousands)						Weighted- Average Exercise Price
Balance at December 31, 2021			13,288						$	9.34
Options granted			10,592						1.26
Options exercised			(15)						0.19
Options forfeited			(4,644)						5.42
Balance at September 30, 2022			19,221						$	5.84
Exercisable as of September 30, 2022			5,302						$	11.71

Schedule of Restricted Stock Units Activity

The following table summarizes the Company’s RSUs activity and related information:

			Number of Units (in thousands)						Weighted- Average Grant- Date Fair Value
Outstanding at December 31, 2021			2,126						$	3.76
Granted			857						1.43
Vested and released			(833)						3.40
Forfeited			(426)						3.18
Outstanding at September 30, 2022			1,724						$	2.92

Schedule of Stock-Based Compensation Expense

The following table presents, by operating expense, the Company’s stock-based compensation expense:

			Three Months Ended September 30,												Nine Months Ended September 30,
			2022						2021						2022						2021
			(In thousands)
Research and development			$	1,432					$	2,207					$	5,195					$	7,125
General and administrative			3,071						3,119						9,631						13,659
Total stock-based compensation expense			$	4,503					$	5,326					$	14,826					$	20,784

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Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement.

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Tabular disclosure of the number and weighted-average grant date fair value for restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock units that were granted, vested, or forfeited during the year.

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Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

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