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Income Taxes (Tables)
 12 Months Ended
Dec. 31, 2022
Income Tax Disclosure [Abstract]  
Schedule of Components of Loss Before Income Taxes The following table presents domestic and foreign components of loss before provision for income taxes:
Years ended December 31,
20222021
(In thousands)
U.S.$(154,002)$(145,375)
Foreign(460)(165)
Loss before income taxes$(154,462)$(145,540)
Schedule of Components of Income Tax Provision The components of the Company’s income tax provision were as follows:
Years ended December 31,
20222021
(In thousands)
Current:
Foreign$74 $— 
Total current tax provision74 — 
Deferred
Foreign— — 
Total deferred tax provision— — 
Total income tax provision$74 $— 
Schedule of Reconciliation of Income Tax Expense Computed Statutory Federal Income Tax and Financial Statements Income tax provision for the years ended December 31, 2022 and 2021 differed from the amounts computed by applying the statutory federal income tax rate of 21% to pretax loss as a result of the following:
Years ended December 31,
20222021
(In thousands)
Federal income tax expense at statutory rate$(32,437)$(30,563)
Stock compensation3,414 1,662 
Non-deductible expenses52 28 
Research and development tax credits(2,529)(2,672)
Change in valuation allowance31,542 41,324 
Foreign rate differential(46)(9)
Impact of internal reorganization103 (9,763)
Other(25)(7)
Total tax provision$74 $— 
Schedule of Deferred Tax Assets The following table presents significant components of the Company’s deferred tax assets and liabilities:
As of December 31,
20222021
(In thousands)
Deferred tax assets:
Net operating loss carryforwards$111,709 $105,509 
Accruals, reserve and other2,053 2,272 
Tax credit carryforwards21,439 16,838 
Stock-based compensation10,705 9,741 
Property and equipment279 — 
Intangibles1,562 1,613 
Lease obligation26,241 24,224 
Capital losses9,850 9,850 
Capitalized costs23,697 — 
Total deferred tax assets before valuation allowance207,535 170,047 
Valuation allowance(188,141)(148,440)
Total deferred tax assets19,394 21,607 
Deferred tax liabilities:
Right-of-use assets(19,394)(20,227)
Property and equipment— (1,380)
Total deferred tax liabilities$(19,394)$(21,607)
Net deferred tax assets$— $— 
Schedule of Unrecognized Tax Benefits A reconciliation of the unrecognized tax benefits is as follows:
Years ended December 31,
20222021
(In thousands)
Unrecognized tax benefits as of the beginning of the year$21,944 $8,677 
Increase related to prior year tax provisions274 10,656 
Increase related to current year tax provisions2,527 2,611 
Unrecognized tax benefits as of the end of the year$24,745 $21,944