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CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY - USD ($)
shares in Thousands, $ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Other Comprehensive Loss
Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2020   97,549      
Beginning balance at Dec. 31, 2020 $ 434,347 $ 10 $ 937,134 $ (261) $ (502,536)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock net of issuance costs (in shares)   121      
Issuance of common stock net of issuance costs 1,685 $ 0 1,685    
Stock-based compensation expense $ 25,194   25,194    
Common stock issued upon exercise of stock options, shares (in shares) 9 9      
Common stock issued upon exercise of stock options $ 51   51    
Common stock issued under employee stock purchase plan (in shares)   397      
Common stock issued under employee stock purchase plan 901   901    
Common stock issued upon release of restricted stock units (in shares)   305      
Net unrealized loss on marketable securities (428)     (428)  
Foreign currency translation adjustment (25)     (25)  
Net loss $ (145,540)       (145,540)
Ending balance (in shares) at Dec. 31, 2021 98,381 98,381      
Ending balance at Dec. 31, 2021 $ 316,185 $ 10 964,965 (714) (648,076)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Stock-based compensation expense $ 20,079   20,079    
Common stock issued upon exercise of stock options, shares (in shares) 15 15      
Common stock issued upon exercise of stock options $ 3   3    
Common stock issued under employee stock purchase plan (in shares)   886      
Common stock issued under employee stock purchase plan 604   604    
Common stock issued upon release of restricted stock units (in shares)   835      
Net unrealized loss on marketable securities (788)     (788)  
Foreign currency translation adjustment (29)     (29)  
Net loss $ (154,536)       (154,536)
Ending balance (in shares) at Dec. 31, 2022 100,117 100,117      
Ending balance at Dec. 31, 2022 $ 181,518 $ 10 $ 985,651 $ (1,531) $ (802,612)