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Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Jun. 30, 2023
Jun. 30, 2022
Income Statement [Abstract]        
License revenue $ 0 $ 0 $ 3,600 $ 0
Operating expenses:        
Research and development 20,599 30,265 41,658 53,229
General and administrative 12,466 13,760 25,246 28,929
Total operating expenses 33,065 44,025 66,904 82,158
Operating loss (33,065) (44,025) (63,304) (82,158)
Other income, net 1,576 283 2,776 527
Net loss before income taxes (31,489) (43,742) (60,528) (81,631)
Income tax provision (21) (19) (38) (38)
Net loss (31,510) (43,761) (60,566) (81,669)
Other comprehensive income (loss):        
Net unrealized gain/(loss) on marketable securities 198 (339) 937 (1,062)
Foreign currency translation adjustment (5) (34) (12) (20)
Comprehensive loss $ (31,317) $ (44,134) $ (59,641) $ (82,751)
Net loss per share — basic (in USD per share) $ (0.31) $ (0.44) $ (0.60) $ (0.83)
Net loss per share — diluted (in USD per share) $ (0.31) $ (0.44) $ (0.60) $ (0.83)
Weighted-average common shares used to compute net loss per share - basic (in shares) 100,768 99,000 100,537 98,799
Weighted-average common shares used to compute net loss per share - diluted (in shares) 100,768 99,000 100,537 98,799