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Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2024 | Jun. 30, 2023
Cash flows from operating activities: |  |
Net loss | $ (43,263) | $ (60,566)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 1,953 | 3,126
Stock-based compensation expense | 8,111 | 9,032
Net accretion of discount on marketable securities | (775) | (1,675)
Non-cash lease expense | 1,029 | 6,936
Other | (9) | (306)
Changes in operating assets and liabilities: |  |
Prepaid expenses and other current assets | 656 | 775
Deposit and other long-term assets and deferred rent receivable | (6,894) | 105
Accounts payable | (111) | (944)
Accrued expenses and other liabilities | (2,639) | (525)
Lease liability | (1,147) | (1,619)
Net cash used in operating activities | (43,089) | (45,661)
Cash flows from investing activities: |  |
Purchases of marketable securities | (49,448) | (20,232)
Maturities of marketable securities | 25,200 | 108,909
Purchases of property and equipment | (106) | (121)
Net cash (used in) provided by investing activities | (24,354) | 88,556
Cash flows from financing activities: |  |
Proceeds from issuance of common stock and pre-funded warrants in private placements, net of issuance costs | 119,361 | 0
Proceeds from issuance of common stock pursuant to option exercises | 139 | 0
Payment of deferred offering costs | 0 | (238)
Proceeds from employee stock purchase plan | 264 | 246
Net cash provided by financing activities | 119,764 | 8
Net increase in cash and cash equivalents and restricted cash | 52,321 | 42,903
Cash and cash equivalents and restricted cash at beginning of period | 76,976 | 70,934
Cash and cash equivalents and restricted cash at end of period | 129,297 | 113,837
Cash and cash equivalents | 127,321 | 111,187
Restricted cash | 1,976 | 2,650
Cash and cash equivalents and restricted cash at end of period | 129,297 | 113,837
Supplemental schedule of noncash investing and financing information |  |
Deferred offering costs included in accounts payable and accrued expenses | 0 | 107
Remeasurement of operating lease right-of-use assets | 0 | 13,711
Property and equipment in accounts payable, accrued expenses and other current liabilities | $ 221 | $ 496

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