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Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Income Statement [Abstract]        
License revenue $ 1,000 $ 0 $ 1,000 $ 3,600
Operating expenses:        
Research and development 20,439 20,740 52,946 62,398
General and administrative 9,782 13,789 24,996 39,035
Total operating expenses 30,221 34,529 77,942 101,433
Operating loss (29,221) (34,529) (76,942) (97,833)
Other income, net 2,087 1,661 6,545 4,437
Net loss before income taxes (27,134) (32,868) (70,397) (93,396)
Income tax provision 0 (17) 0 (55)
Net loss (27,134) (32,885) (70,397) (93,451)
Other comprehensive gain (loss):        
Net unrealized gain on marketable securities 241 66 198 1,003
Foreign currency translation adjustment 16 (12) 7 (24)
Comprehensive loss $ (26,877) $ (32,831) $ (70,192) $ (92,472)
Net loss per share — basic (in USD per share) $ (1.30) $ (3.26) $ (3.63) $ (9.28)
Net loss per share — diluted (in USD per share) $ (1.30) $ (3.26) $ (3.63) $ (9.28)
Weighted-average common shares used to compute net loss per share - basic (in shares) 20,876 10,100 19,408 10,069
Weighted-average common shares used to compute net loss per share - diluted (in shares) 20,876 10,100 19,408 10,069