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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 6 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2024
Jun. 30, 2024
Mar. 31, 2024
Sep. 30, 2023
Jun. 30, 2023
Mar. 31, 2023
Jun. 30, 2024
Jun. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Dec. 31, 2024
Dec. 31, 2023
Income Statement [Abstract]                        
License revenue $ 1,000     $ 0 $ 0 $ 3,600   $ 3,600 $ 1,000 $ 3,600 $ 1,000 $ 3,600
Operating expenses:                        
Research and development 20,439 $ 17,097 $ 15,410 20,740 20,599 20,869 $ 32,507 41,468 52,946 62,208 77,041 77,486
General and administrative 14,999 15,807 13,789 14,319 13,481 15,586 29,596 29,067 44,595 43,386 63,118 55,056
Total operating expenses 35,438 32,904 29,199 35,059 34,080 36,455 62,103 70,535 97,541 105,594 140,159 132,542
Operating loss (34,438) (32,904) (29,199) (35,059) (34,080) (32,855) (62,103) (66,935) (96,541) (101,994) (139,159) (128,942)
Other income, net 2,087 2,406 2,052 1,661 1,576 1,200 4,458 2,776 6,545 4,437 8,232 5,748
Net loss before income taxes       (33,398) (32,504) (31,655)   (64,159)   (97,557) (130,927) (123,194)
Income tax benefit       (17) (21) (17)   (38)   (55) 0 1,078
Net loss (32,351) (30,498) (27,147) (33,415) (32,525) (31,672) (57,645) (64,197) (89,996) (97,612) (130,927) (122,116)
Other comprehensive gain (loss):                        
Net unrealized gain on marketable securities 241 (2) (41) 66 198 739 (43) 937 198 1,003 105 1,057
Foreign currency translation adjustment 16 10 (19) (12) (5) (7) (9) (12) 7 (24) (39) 1
Comprehensive loss $ (32,094) $ (30,490) $ (27,207) $ (33,361) $ (32,332) $ (30,940) $ (57,697) $ (63,272) $ (89,791) $ (96,633) $ (130,861) $ (121,058)
Net loss per share - basic (in USD per share) $ (1.55) $ (1.46) $ (1.65) $ (3.31) $ (3.23) $ (3.16) $ (3.08) $ (6.39) $ (4.64) $ (9.69) $ (6.62) $ (12.11)
Net loss per share - diluted (in USD per share) $ (1.55) $ (1.46) $ (1.65) $ (3.31) $ (3.23) $ (3.16) $ (3.08) $ (6.39) $ (4.64) $ (9.69) $ (6.62) $ (12.11)
Weighted-average common shares outstanding - basic (in shares) 20,876 20,852 16,479 10,099 10,076 10,030 18,713 10,053 19,408 10,069 19,782 10,082
Weighted-average common shares outstanding - diluted (in shares) 20,876 20,852 16,479 10,099 10,076 10,030 18,713 10,053 19,408 10,069 19,782 10,082