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ORGANIZATION AND BASIS OF PRESENTATION (Tables)

12 Months Ended

Dec. 31, 2022

ORGANIZATION AND BASIS OF PRESENTATION

Summary of principal subsidiaries

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​	​	​	​	​	​	Percentage of legal	​	​
​	​	Date of	​	Place of	​	ownership	​	​
Entity		incorporation		incorporation		by the Company		Principal activities
Adagene (Hong Kong) Limited	​	December 12, 2011		Hong Kong		100	%	Investment holding
Adagene Incorporated	​	September 20, 2017		The United States of America		100	%	Research and development of innovative medicines
Adagene (Suzhou) Limited	​	February 28, 2012		The People’s Republic of China (“PRC” or “China”)		100	%	Research and development of innovative medicines
Adagene Australia PTY Ltd.	​	May 30, 2018	​	Australia	​	100	%	Research and development of innovative medicines
Adagene PTE. Ltd.	​	March 27, 2020	​	Singapore	​	100	%	Research and development of innovative medicines
Adagene AG	​	August 31, 2020		Switzerland		100	%	Research and development of innovative medicines
Adagene Project C1 PTE. Ltd.	​	March 25, 2022		Singapore		100	%	Research and development of innovative medicines

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The tabular disclosure of principal subsidiaries.

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