    <SEC-DOCUMENT>0001104659-24-041120-index.html : 20240329
    <SEC-HEADER>0001104659-24-041120.hdr.sgml : 20240329
    <ACCEPTANCE-DATETIME>20240329153330
    ACCESSION NUMBER:		0001104659-24-041120
    CONFORMED SUBMISSION TYPE:	424B5
    PUBLIC DOCUMENT COUNT:		5
    FILED AS OF DATE:		20240329
    DATE AS OF CHANGE:		20240329

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Adagene Inc.
    		CENTRAL INDEX KEY:			0001818838
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			E9
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		424B5
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-264486
    		FILM NUMBER:		24803955

    	BUSINESS ADDRESS:
    		STREET 1:		4F, BUILDING C14, NO. 218, XINGHU STREET
    		STREET 2:		SUZHOU INDUSTRIAL PARK
    		CITY:			JIANGSU
    		STATE:			F4
    		ZIP:			00000
    		BUSINESS PHONE:		86-512-87773632

    	MAIL ADDRESS:
    		STREET 1:		4F, BUILDING C14, NO. 218, XINGHU STREET
    		STREET 2:		SUZHOU INDUSTRIAL PARK
    		CITY:			JIANGSU
    		STATE:			F4
    		ZIP:			00000
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>424B5
    <SEQUENCE>1
    <FILENAME>tm2213007-9_424b5.htm
    <DESCRIPTION>424B5
    <TEXT>
    Document 1 - file: tm2213007-9_424b5.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>lg_adagene-4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: lg_adagene-4clr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>tm2213007d1-pc_neobody4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: tm2213007d1-pc_neobody4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>tm2213007d1-tbl_program4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: tm2213007d1-tbl_program4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>tm2213007d1-fc_corpobw.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: tm2213007d1-fc_corpobw.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>