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Segment Reporting - Summary of Disaggregated Segment Expenses Split between R&D and G&A Costs (Details) - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2026 | Mar. 31, 2025
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |
Research and development expenses | $ 13,606 | $ 23,888
General and administrative expenses | 5,360 | 7,932
Loss from operations | (18,966) | (31,820)
Interest income | 1,182 | 1,483
Interest expense | (331) | (406)
Other income (expense), net | 188 | (11)
Net loss | (17,927) | (30,754)
Operating Segments | Clinical and Development Costs |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |
Research and development expenses | 8,280 | 10,537
Operating Segments | Preclinical Costs |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |
Research and development expenses | (65) | 1,238
Operating Segments | Personnel and Related Costs |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |
Research and development expenses | 3,175 | 7,563
General and administrative expenses | 1,841 | 2,825
Operating Segments | Stock-based Compensation Expense |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |
Research and development expenses | 1,201 | 3,005
General and administrative expenses | 1,308 | 2,211
Operating Segments | Other Research Costs |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |
Research and development expenses | 1,015 | 1,545
Operating Segments | Other General and Administrative Costs |  |
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] |  |
General and administrative expenses | $ 2,211 | $ 2,896

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