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Note 2 - Significant Accounting Policies - Stock Option Valuation Assumptions (Details) - $ / shares
3 Months Ended 9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Dividend yield 0.00% 0.00% 0.00% 0.00%
Expected volatility 87.00%      
Weighted-average grant date fair value per share (in dollars per share) $ 12.46 $ 5.66 $ 12.05 $ 5.14
Minimum [Member]        
Expected volatility   90.00% 87.00% 80.00%
Risk-free interest rate 0.33% 1.59% 0.33% 1.59%
Expected life (Year) 5 years 4 months 17 days 5 years 4 months 17 days 5 years 4 months 17 days 5 years 4 months 17 days
Maximum [Member]        
Expected volatility   91.00% 91.00% 91.00%
Risk-free interest rate 0.44% 1.89% 1.87% 2.64%
Expected life (Year) 6 years 3 months 6 years 3 months 10 years 10 years