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Note 2 - Significant Accounting Policies (Details Textual) $ in Thousands, shares in Millions	3 Months Ended	12 Months Ended
	Mar. 31, 2022 USD ($)	Dec. 31, 2021 USD ($) shares	Dec. 31, 2020 shares
Impairment of Long-Lived Assets Held-for-use	$ 0
Number of Operating Segments	1
Furniture and Fixtures [Member]
Property, Plant and Equipment, Useful Life (Year)	7 years
Office Equipment [Member]
Property, Plant and Equipment, Useful Life (Year)	5 years
Equipment [Member]
Property, Plant and Equipment, Useful Life (Year)	5 years
Vehicles [Member]
Property, Plant and Equipment, Useful Life (Year)	5 years
Mobile Facility [Member]
Property, Plant and Equipment, Useful Life (Year)	27 years 6 months
Building [Member]
Property, Plant and Equipment, Useful Life (Year)	39 years
Fair Value, Recurring [Member]
Assets, Fair Value Disclosure	$ 0	$ 0
Financial and Nonfinancial Liabilities, Fair Value Disclosure	$ 0	$ 0
Janssen [Member] \| Manufacturing Revenue [Member]
Treasury Stock, Shares, Acquired (in shares) \| shares		4.5	4.5