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Note 2 - Significant Accounting Policies (Tables)

6 Months Ended

Jun. 30, 2022

Notes Tables

Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]

		Three Months Ended								Six Months Ended
		June 30,								June 30,
		2022				2021				2022				2021
Research and development		$	979			$	433			$	1,969			$	796
General and administrative			469				534				927				1,046
Cost of goods sold			-				73				-				134
Total share-based compensation expense		$	1,448			$	1,040			$	2,896			$	1,976

Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

		Three Months Ended								Six Months Ended
		June 30,								June 30,
		2022				2021				2022				2021
Dividend yield			-				-				-				-
Expected volatility			83%			84%	-	85%		82%	-	83%		84%	-	86%
Risk-free interest rate		2.5%	-	3.5%		0.9%	-	1.1%		1.5%	-	3.5%		0.5%	-	1.1%
Expected life (in years)		5.38	-	6.25		5.38	-	6.25		5.38	-	6.25		5.38	-	6.25
Weighted-average grant date fair value per share			5.43				11.12				5.53				11.49

X

- Definition

Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement.

+ References

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-SubTopic 10
-Section 50
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- Definition

Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

+ References

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (f)(2)
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