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Commitments and Contingencies, Wistar License Agreement (Details) - Wistar License Agreement [Member] | 12 Months Ended
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Dec. 31, 2017 Extension
Wistar License Agreement [Abstract] |
Maximum reduction in royalty payments | 50.00%
Number of one-year extensions | 3
Minimum [Member] |
Wistar License Agreement [Abstract] |
Royalty rates on amount of cumulative net sales | 3.00%
Maximum [Member] |
Wistar License Agreement [Abstract] |
Royalty rates on amount of cumulative net sales | 5.00%

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- Definition The number of one-year extensions that may be purchased is sales of a licensed product do not commence by the specified date. + References No definition available. + Details
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- Definition The percentage of royalty payments under a contractual arrangement such as payment for mineral and drilling rights and use of technology or intellectual property. + References No definition available. + Details
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- Details
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