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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2017
Income Taxes [Abstract]  
Components of Deferred Tax Assets and Liabilities
The primary components of the deferred tax assets and liabilities at December 31, 2017 and 2016 were as follows (in thousands):

  
2017
  
2016
 
Deferred liabilities:
      
Available-for-sale securities
 
$
-
 
 
$
(761
)
Total deferred tax liabilities
  
-
 
  
(761
)
         
Deferred tax assets:
        
Net operating loss carryforwards
  
11,414
   
11,730
 
Research and development credit carryforwards
  
2,141
   
1,765
 
Patents and fixed assets
  
268
   
179
 
Stock-based compensation and accrued payroll
  
1,260
   
1,041
 
Valuation Allowance
  
(15,083
)
  
(13,954
)
Total deferred tax assets
  
-
   
761
 
Net deferred tax asset (liability)
 
$
-
  
$
-
 
Income Tax Reconciliation
Income taxes differed from the amounts computed by applying the U.S. federal income tax of 34% to pretax losses from operations as a result of the following:

  
Year Ended December 31,
 
  
2017
  
2016
  
2015
 
Computed tax benefit at federal statutory rate
  34
%
 
  34
%
 
  34
%
 
Re-rate of federal net deferred tax assets
  (35)
%
 
  0
%
 
  0
%
 
Permanent differences
  (8)
%
 
  (1)
%
 
  (9)
%
 
State tax benefit
  3
%
 
  2
%
 
  15
%
 
Research and development credits
  1
%
 
  2
%
 
  2
%
 
Other
  0
%
 
  7
%
 
  3
%
 
Adjusted basis for available-for-sale-securities   11%    0%    0% 
Change in valuation allowance
  (6)
%
 
  (44)
%
 
  (45)
%
 
   -
%
 
  -
%
 
  -
%