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Novartis Collaboration and License Agreement (the "Novartis Agreement") - Additional Information (Details) - Novartis | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2020 USD ($) | Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($) | Dec. 31, 2019 USD ($) research
Novartis Agreement |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Proceeds from upfront non-refundable license fee |  |  |  | $ 50,000,000
Revenue recognized from related party |  | $ 2,000,000 | $ 41,800,000 |
Receivable from related party transactions |  | 2,000,000 | 9,300,000 |
Contract assets |  | 0 | 0 |
Contract liabilities |  | 0 | 0 |
Novartis Agreement | Achievement of First Patient Dosing Milestone |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Revenue recognized from related party |  | 391,000,000 | $ 25,000,000 |
Novartis Agreement | Research and Development |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Revenue recognized from related party | $ 16,800,000 | 7,600,000 |  | 7,100,000
Novartis Agreement | License Fee |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Revenue recognized from related party |  |  |  | $ 50,000,000
Novartis Agreement | Maximum |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Number of Integrin research targets | research |  |  |  | 3
Collaboration and license agreement, integrin research targets amount |  |  |  | $ 416,000,000
Novartis Agreement RD For PLN-1474 |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Transaction price of Novartis agreement |  | 20,000,000 |  | 19,600,000
Novartis Agreement RD For Integrin Research Targets | Research and Development |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Transaction price of Novartis agreement |  | $ 13,400,000 |  | $ 13,400,000

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