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Statements of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019
Cash flows from operating activities: |  |  |
Net loss | $ (97,263) | $ (41,533) | $ (631)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Depreciation expense | 1,535 | 1,310 | 1,113
Stock-based compensation expense | 10,437 | 3,895 | 1,829
Noncash lease expense | 1,669 | 0 | 0
Other | 1,262 | 266 | 0
Changes in operating assets and liabilities: |  |  |
Tax credit receivable | 0 | 250 | 167
Accounts receivable | 7,281 | (2,227) | (7,052)
Prepaid expenses and other current assets | (2,266) | (2,756) | (1,458)
Other non-current assets | 70 | (70) | 232
Accounts payable | 891 | 922 | (1,255)
Accrued liabilities | 2,695 | 2,689 | 4,255
Operating lease liabilities | (1,754) | 0 | 0
Deferred rent and other long-term liabilities | 0 | (17) | 50
Net cash used in operating activities | (75,443) | (37,271) | (2,750)
Cash flows from investing activities: |  |  |
Purchase of short-term investments | (219,887) | (322,605) | (51,713)
Accretion on short-term investments | 0 | 0 | (254)
Maturity of short-term investments | 295,539 | 113,271 | 35,000
Purchase of property and equipment | (1,953) | (1,532) | (964)
Net cash used in investing activities | 73,699 | (210,866) | (17,931)
Cash flows from financing activities: |  |  |
Proceeds from issuance of common stock upon initial public offering, net of issuance costs | 0 | 150,751 | 0
Proceeds from issuance of common stock upon completion of private placement | 0 | 10,000 | 0
Proceeds from issuance of Series C preferred stock, net of issuance costs | 0 | 52,019 | 47,947
Proceeds from issuances of common stock | 2,984 | 442 | 174
Payment of deferred offering costs | (457) | 0 | (2,582)
Net cash provided by financing activities | 2,527 | 213,212 | 45,539
Net increase (decrease) in cash and cash equivalents | 783 | (34,925) | 24,858
Cash and cash equivalents at beginning of period | 50,882 | 85,807 | 60,949
Cash and cash equivalents at end of period | 51,665 | 50,882 | 85,807
Supplemental disclosures of noncash investing and financing activities: |  |  |
Purchase of property and equipment in accounts payable and accrued liabilities | 57 | 188 | 159
Reclassification of restricted stock awards from liabilities to common stock upon vesting | 9 | 11 | 30
Accretion to redemption value and dividends on redeemable convertible preferred stock | 0 | 0 | 6,225
Deferred offering costs in accounts payable and accrued liabilities | 0 | 0 | 230
Net unrealized loss on short-term investments | $ (169) | $ (31) | $ (1)

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