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Income Taxes - Summary of Reconciliation of U.S. Federal Statutory Income Tax Rate to Company’s Effective Income Tax Rate (Details)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Income Tax Disclosure [Abstract]      
Income tax computed at federal statutory rate 21.00% 21.00% 21.00%
State taxes, net of federal tax benefit 7.70% 7.40% 2.70%
General business credit—federal 5.30% 5.30% 295.90%
Stock-based compensation (0.70%) (1.00%) (50.00%)
Other permanent differences (0.10%) (0.10%) (2.40%)
Change in valuation allowance (33.20%) (32.60%) (267.70%)
Effective income tax rate 0.00% 0.00% (0.50%)