<SEC-DOCUMENT>0001140361-22-033661.txt : 20220916
<SEC-HEADER>0001140361-22-033661.hdr.sgml : 20220916
<ACCEPTANCE-DATETIME>20220916180513
ACCESSION NUMBER:		0001140361-22-033661
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20220914
FILED AS OF DATE:		20220916
DATE AS OF CHANGE:		20220916

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Knobil Katharine
		CENTRAL INDEX KEY:			0001768011

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39303
		FILM NUMBER:		221249007

	MAIL ADDRESS:	
		STREET 1:		C/O KALEIDO BIOSCIENCES, INC.
		STREET 2:		65 HAYDEN AVE.
		CITY:			LEXINGTON
		STATE:			MA
		ZIP:			02421

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PLIANT THERAPEUTICS, INC.
		CENTRAL INDEX KEY:			0001746473
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				474272481
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		260 LITTLEFIELD AVENUE
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080
		BUSINESS PHONE:		650-481-6770

	MAIL ADDRESS:	
		STREET 1:		260 LITTLEFIELD AVENUE
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>form3.xml
<DESCRIPTION>FORM 3
<TEXT>
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    <periodOfReport>2022-09-14</periodOfReport>

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    <issuer>
        <issuerCik>0001746473</issuerCik>
        <issuerName>PLIANT THERAPEUTICS, INC.</issuerName>
        <issuerTradingSymbol>PLRX</issuerTradingSymbol>
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            <rptOwnerCik>0001768011</rptOwnerCik>
            <rptOwnerName>Knobil Katharine</rptOwnerName>
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            <rptOwnerStreet1>C/O PLIANT THERAPEUTICS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>260 LITTLEFIELD AVENUE</rptOwnerStreet2>
            <rptOwnerCity>SOUTH SAN FRANCISCO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>94080</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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            <isDirector>true</isDirector>
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    <remarks>Exhibit List - Exhibit 24 - Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Mike Ouimette, attorney-in-fact</signatureName>
        <signatureDate>2022-09-16</signatureDate>
    </ownerSignature>
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<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>brhc10041953_ex24.htm
<DESCRIPTION>EXHIBIT 24
<TEXT>
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      <div style="text-align: right; color: #000000; font-family: 'Times New Roman', serif; font-size: 10pt; font-weight: bold;">Exhibit 24</div>
      <div><br>
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      <div style="text-align: center; color: #000000; font-family: 'Times New Roman', serif; font-size: 10pt; font-weight: bold;">LIMITED POWER OF ATTORNEY</div>
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      <div style="text-align: justify; text-indent: 36pt; color: #000000; font-family: 'Times New Roman', serif; font-size: 10pt;">The undersigned hereby constitutes and appoints each of Bernard Coulie, Keith Cummings, Johannes (Hans) Hull, Mike Ouimette,
        and Sharon Flanagan, signing singly, and with full power of substitution, the undersigned&#8217;s true and lawful attorney-in-fact to:</div>
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      <div style="text-align: justify; text-indent: 36pt;"><font style="font-family: 'Times New Roman', serif; font-size: 10pt; color: #000000;">(1)</font><font id="TRGRRTFtoHTMLTab" style="text-indent: 0px; font-size: 5.14pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman', serif; font-size: 10pt; color: #000000;">execute for and on behalf of the undersigned, in the undersigned&#8217;s capacity as officer and/or director of Pliant Therapeutics, Inc., a Delaware corporation (the
          &#8220;Company&#8221;), from time to time the following U.S. Securities and Exchange Commission (&#8220;SEC&#8221;) forms: (i) Form ID, including any attached documents (such as Update Passphrase Authentication), to effect the assignment of codes to the undersigned to
          be used in the transmission of information to the SEC using the EDGAR System; (ii) Form 3, Initial Statement of Beneficial Ownership of Securities, including any attached documents; (iii) Form 4, Statement of Changes in Beneficial Ownership of
          Securities, including any attached documents; (iv) Form 5, Annual Statement of Beneficial Ownership of Securities in accordance with Section 16(a) of the Securities Exchange Act of 1934, as amended, and the rules thereunder, including any
          attached documents; (v) Schedules 13D and 13G; and (vi) amendments of each thereof, in accordance with the Securities Exchange Act of 1934, as amended, and the rules thereunder, including any attached documents;</font></div>
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      <div style="text-align: justify; text-indent: 36pt;"><font style="font-family: 'Times New Roman', serif; font-size: 10pt; color: #000000;">(2)</font><font id="TRGRRTFtoHTMLTab" style="text-indent: 0px; font-size: 5.14pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman', serif; font-size: 10pt; color: #000000;">do and perform any and all acts for and on behalf of the undersigned which may be necessary or desirable to complete and execute any such Form 3, 4 or 5, Schedule 13D
          or 13G, or any amendment(s) thereto and timely file such form(s) with the SEC and any securities exchange, national association or similar authority; and</font></div>
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      <div style="text-align: justify; text-indent: 36pt;"><font style="font-family: 'Times New Roman', serif; font-size: 10pt; color: #000000;">(3)</font><font id="TRGRRTFtoHTMLTab" style="text-indent: 0px; font-size: 5.14pt;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</font><font style="font-family: 'Times New Roman', serif; font-size: 10pt; color: #000000;">take any other action of any type whatsoever in connection with the foregoing which, in the opinion of such attorney-in-fact, may be of benefit to, in the best
          interest of, or legally required by, the undersigned, it being understood that the documents executed by such attorney-in-fact on behalf of the undersigned pursuant to this Power of Attorney shall be in such form and shall contain such terms and
          conditions as such attorney-in-fact may approve in such attorney-in-fact&#8217;s discretion.</font></div>
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      <div style="text-align: justify; text-indent: 36pt; color: #000000; font-family: 'Times New Roman', serif; font-size: 10pt;">The undersigned hereby grants to each such attorney-in-fact, acting singly, full power and authority to do and perform any
        and every act and thing whatsoever requisite, necessary or proper to be done in the exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full
        power of substitution or revocation, hereby ratifying and confirming all that such attorney-in-fact, or such attorney-in-fact&#8217;s substitute or substitutes, shall lawfully do or cause to be done by virtue of this power of attorney and the rights and
        powers herein granted.&#160; The undersigned acknowledges that the foregoing attorneys-in-fact, in serving in such capacity at the request of the undersigned, are not assuming, nor is the Company assuming, any of the undersigned&#8217;s responsibilities to
        comply with Section 16 or Regulation 13D-G of the Securities Exchange Act of 1934, as amended.&#160; The undersigned hereby agrees to indemnify the attorneys-in-fact and the Company from and against any demand, damage, loss, cost or expense arising from
        any false or misleading information provided by the undersigned to the attorneys-in-fact.</div>
      <div><br>
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      <div style="text-align: justify; text-indent: 36pt; color: #000000; font-family: 'Times New Roman', serif; font-size: 10pt;">This Power of Attorney shall remain in full force and effect until the undersigned is no longer required to file such forms
        with respect to the undersigned&#8217;s holdings of and transactions in securities issued by the Company, unless earlier revoked by the undersigned in a signed writing delivered to the foregoing attorneys-in-fact.&#160; This Power of Attorney supersedes any
        prior power of attorney in connection with the undersigned&#8217;s capacity as an officer and/or director of the Company.&#160; This Power of Attorney shall expire as to any individual attorney-in-fact if such attorney-in-fact ceases to be an employee of, or
        legal counsel to, the Company.</div>
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      <div style="text-align: justify; text-indent: 36pt; color: #000000; font-family: 'Times New Roman', serif; font-size: 10pt;">IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of&#160; 08/21/2022.</div>
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            <td style="width: 50%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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              <div style="font-family: 'Times New Roman', serif; font-size: 10pt;"><font style="color: #000000;">/s/ </font>Katharine Knobil, M.D</div>
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              <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 10pt;">Signature</div>
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              <div style="font-family: 'Times New Roman', serif; font-size: 10pt;">Katharine Knobil, M.D.</div>
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            <td style="width: 10%; vertical-align: top; padding-bottom: 2px;">&#160;</td>
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              <div style="color: #000000; font-family: 'Times New Roman', serif; font-size: 10pt;">Print Name</div>
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