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Organization and Summary of Significant Accounting Policies - Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share for Out of Money Potential Common Shares (Detail) - shares
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Out of the money options and warrants excluded 225,324 437,443 505,491
Stock Options with an Exercise Price of $3.59 per Share [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Out of the money options and warrants excluded   7,521  
Stock Options With an Exercise Price of $12.48 per Share [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Out of the money options and warrants excluded 137,666 137,666 137,667
Stock Options With an Exercise Price of $12.84 per Share [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Out of the money options and warrants excluded 4,167 4,167 4,167
Stock Options With an Exercise Price of $26.40 per Share [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Out of the money options and warrants excluded 75,158 75,158 79,370
Stock Options With an Exercise Price of $32.76 per Share [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Out of the money options and warrants excluded     53,706
Stock Options With an Exercise Price of $34.68 per Share [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Out of the money options and warrants excluded   73,765 78,707
Stock Options With an Exercise Price of $39.00 per Share [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Out of the money options and warrants excluded 8,333 8,333 8,333
Stock Options With an Exercise Price of $41.16 per Share [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Out of the money options and warrants excluded   833 3,333
Stock Options With an Exercise Price of $42.00 per Share [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Out of the money options and warrants excluded   8,333 8,333
Stock Options With an Exercise Price of $46.80 per Share [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Out of the money options and warrants excluded   1,667 1,667
Stock Options With an Exercise Price of $3.52 per Share [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Out of the money options and warrants excluded   120,000  
Stock Options With an Exercise Price of $43.20 per Share [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Out of the money options and warrants excluded     130,208