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Summary of Significant Accounting Policies - Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share for Out of Money Potential Common Shares (Parenthetical) (Detail) - $ / shares
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Warrants exercise price per share $ 3.52   $ 3.52  
Stock Options With an Exercise Price of $12.48 per Share [Member]        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Stock options exercise price per share 12.48 $ 12.48 12.48 $ 12.48
Stock Options With an Exercise Price of $12.84 per Share [Member]        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Stock options exercise price per share 12.84 12.84 12.84 12.84
Stock Options With an Exercise Price of $26.40 per Share [Member]        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Stock options exercise price per share 26.40 26.40 26.40 26.40
Stock Options With an Exercise Price of $34.68 per Share [Member]        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Stock options exercise price per share 34.68 34.68 34.68 34.68
Stock Options With an Exercise Price of $39.00 per Share [Member]        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Stock options exercise price per share 39.00 39.00 39.00 39.00
Stock Options With an Exercise Price of $41.16 per Share [Member]        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Stock options exercise price per share 41.16 41.16 41.16 41.16
Stock Options With an Exercise Price of $42.00 per Share [Member]        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Stock options exercise price per share 42.00 42.00 42.00 42.00
Warrants With an Exercise Price of $12.00 per Share [Member]        
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Warrants exercise price per share $ 12 $ 12 $ 12 $ 12