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License Agreement - Columbia - Additional Information (Details) - USD ($) |  | 1 Months Ended | 3 Months Ended | 9 Months Ended | 96 Months Ended |
--- | --- | --- | --- | --- | --- | ---
Oct. 03, 2019 | Mar. 31, 2019 | Jan. 31, 2019 | Oct. 31, 2016 | Sep. 30, 2024 | Sep. 30, 2023 | Sep. 30, 2024 | Sep. 30, 2023 | Sep. 30, 2024 | Dec. 31, 2023
Agreements |  |  |  |  |  |  |  |  |  |
Research and development |  |  |  |  | $ 14,828,000 | $ 10,785,000 | $ 37,049,000 | $ 38,602,000 |  |
General and administrative |  |  |  |  | 15,037,000 | 4,710,000 | 34,683,000 | 15,585,000 |  |
Operating expenses |  |  |  |  | 29,865,000 | 15,495,000 | 71,732,000 | 54,187,000 |  |
Accrued expenses and other current liabilities |  |  |  |  | 13,489,000 |  | 13,489,000 |  | $ 13,489,000 | $ 15,286,000
Accounts payable |  |  |  |  | 2,837,000 |  | 2,837,000 |  | 2,837,000 | 1,742,000
License Agreements and Research Services Agreements | Columbia University |  |  |  |  |  |  |  |  |  |
Agreements |  |  |  |  |  |  |  |  |  |
Operating expenses |  |  |  |  | 100,000 | $ 0 | 300,000 | $ 100,000 | 3,200,000 |
Accrued expenses and other current liabilities |  |  |  |  | 100,000 |  | 100,000 |  | 100,000 | 29,000
Accounts payable |  |  |  |  | $ 0 |  | $ 0 |  | $ 0 | $ 0
2016 license agreement | Columbia University |  |  |  |  |  |  |  |  |  |
Agreements |  |  |  |  |  |  |  |  |  |
Percentage of outstanding common stock issued |  |  |  | 5.00% |  |  |  |  |  |
Fair value of stock issued |  |  |  | $ 500,000 |  |  |  |  |  |
Written notice period for termination of agreement |  |  |  | 90 days |  |  |  |  |  |
Written notice period for termination of agreement, uncured material breach |  |  |  | 30 days |  |  |  |  |  |
Extended written notice period for termination of agreement, attempt to cure material breach |  |  |  | 90 days |  |  |  |  |  |
2016 license agreement | Columbia University | Minimum |  |  |  |  |  |  |  |  |  |
Agreements |  |  |  |  |  |  |  |  |  |
Percentage of sublicensing revenue, if sublicenses rights granted |  |  |  | 10.00% |  |  |  |  |  |
2016 license agreement | Columbia University | Maximum |  |  |  |  |  |  |  |  |  |
Agreements |  |  |  |  |  |  |  |  |  |
Payment on achievement of specified development and regulatory milestones |  |  |  | $ 1,300,000 |  |  |  |  |  |
Payment on achievement of specified level of aggregate annual net sales |  |  |  | $ 1,000,000 |  |  |  |  |  |
Percentage of sublicensing revenue, if sublicenses rights granted |  |  |  | 20.00% |  |  |  |  |  |
2019 license agreement | Columbia University | Maximum |  |  |  |  |  |  |  |  |  |
Agreements |  |  |  |  |  |  |  |  |  |
Payment on achievement of specified development and regulatory milestones |  |  | $ 1,300,000 |  |  |  |  |  |  |
Payment on achievement of specified level of aggregate annual net sales |  |  | $ 1,000,000 |  |  |  |  |  |  |
2019 research agreement | Columbia University |  |  |  |  |  |  |  |  |  |
Agreements |  |  |  |  |  |  |  |  |  |
Agreement term |  | 12 months |  |  |  |  |  |  |  |
PI3k Research agreement | Columbia University |  |  |  |  |  |  |  |  |  |
Agreements |  |  |  |  |  |  |  |  |  |
Agreement term | 18 months |  |  |  |  |  |  |  |  |

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