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Share-based Compensation (Tables)
3 Months Ended
Sep. 30, 2019
Share-Based Compensation Expense for Stock Awards
Total share-based compensation expense for all stock awards consists of the following, (in thousands):
 
   
Three Months Ended
September 30,
 
   
2019
   
2018
 
Research and development
  $781   $630 
General and administrative
   1,332    1,307 
   
 
 
   
 
 
 
Total share-based compensation
  $ 2,113   $ 1,937 
   
 
 
   
 
 
 
Summary of Stock Option Activity and Related Data
Stock option activity for the three months ended September 30, 2019 was as follows:
 
   
Number of
Options
   
Weighted-
Average
Exercise Price
   
Weighted-Average

Remaining Contractual
Term (in years)
   
Aggregate
Intrinsic Value
 
Outstanding at June 30, 2019
   8,356,961   $ 3.20           
Granted
   3,083,333    2.50           
Exercised
   (46,667   1.54           
Forfeited / Cancelled
   (49,186   1.81           
Expired
   (527,080   6.89           
   
 
 
                
Outstanding at September 30, 2019
   10,817,361    2.83    8.5   $501,818 
   
 
 
                
Vested and exercisable at September 30, 2019
   4,114,253    2.52    7.3   $ 428,455 
Fair Value of Stock Options Weighted-Average Assumptions Used
The following weighted-average assumptions were used to determine the fair value of options granted during the period:
 
   
Three Months Ended
September 30,
 
   
2019
  
2018
 
Risk-free interest rate
   1.8  2.8
Expected life (years)
   6.0   6.0 
Expected volatility
   73.6  86.0
Dividend yield
   0.0  0.0
Weighted-average grant date fair value
  $1.63  $3.11