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License Agreements - Additional Information (Detail) - USD ($) | 1 Months Ended | 6 Months Ended |  |
--- | --- | --- | --- | ---
Sep. 30, 2017 | Dec. 31, 2021 | Dec. 31, 2020 | Jun. 30, 2021 | May 31, 2020
Related Party Transaction [Line Items] |  |  |  |  |
Milestone payments payable amount |  | $ 20,000,000.0 |  |  |
Performance obligation revenue recognised |  | 1,264,000 | $ 4,260,000 |  |
Kyowa Kirin Co |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Total upfront payment receivable for grant of rights |  |  |  |  | $ 100,000,000.0
Kyowa Kirin Co | Potential Payments on Achievement of Development Regulatory and Commercial Milestones | Maximum |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Milestone payment receivable amount |  | 582,500,000 |  |  |
Presage License Agreement | Presage Biosciences, Inc. |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Compensation payable for grant of rights | $ 4,900,000 |  |  |  |
Payment for license | 2,900,000 |  |  |  |
Presage License Agreement | Presage Biosciences, Inc. | Incremental Payment |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Compensation payable for grant of rights | 2,000,000.0 |  |  |  |
Presage License Agreement | Presage Biosciences, Inc. | Potential Payments on Achievement of Development Regulatory and Commercial Milestones |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Milestone payment receivable amount | $ 179,000,000 |  |  |  |
Kkc Agreements [Member] | Kyowa Kirin Co |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Upfront payment |  | 100,000,000.0 |  |  |
Transaction price relating to the performance obligation |  | 191,500,000 |  |  |
Expected milestone payment receivable |  | 20,000,000.0 |  |  |
Estimated development cost sharing recovered through earnings |  | 66,300,000 |  |  |
Deferred revenue |  | 5,200,000 |  |  |
Kkc Agreements [Member] | Kyowa Kirin Co | Ex US License |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Performance obligation revenue recognised |  | 21,000,000.0 |  |  |
License Obligation Account Transaction Price Allocated |  | 64,500,000 |  |  |
Kkc Agreements [Member] | Kyowa Kirin Co | Development Services |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Deferred revenue |  | 33,400,000 |  | $ 14,700,000 |
Kkc Agreements [Member] | Kyowa Kirin Co | Maximum |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Estimated development cost sharing recovered through earnings |  | $ 228,500 |  |  |

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