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v3.22.1

Commitment and Contingencies (Details) | 1 Months Ended | 3 Months Ended | 12 Months Ended |  |  |
--- | --- | --- | --- | --- | --- | ---
Mar. 31, 2020 USD ($) | Nov. 30, 2015 USD ($) shares | Apr. 30, 2021 USD ($) shares | Dec. 31, 2021 USD ($) shares | Dec. 31, 2020 USD ($) shares | Feb. 01, 2022 USD ($) | Aug. 31, 2021 USD ($) $ / shares shares | Jun. 30, 2021 USD ($)
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Rent expense |  |  |  | $ 10,000 | $ 10,000 |  |  |
Subsequent event |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Sublease minimum payments due |  |  |  |  |  | $ 100,000 |  |
Series A Preferred Stock |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Temporary equity new shares issued (in shares) | shares |  |  | 738,445 | 738,445 | 132,537 |  |  |
Temporary equity, stock issued for services (in shares) | shares |  |  |  | 418,559 |  |  |  |
Temporary equity, stock issued for services |  |  |  | $ 2,837,832 |  |  |  |
Drexel University | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Percentage of payments as to credits accounts payable |  | 0.50 |  |  |  |  |  |
Drexel University | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Minimum |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Milestone payment |  | $ 10,000 |  |  |  |  |  |
Drexel University | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Maximum |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Milestone payment |  | $ 200,000 |  |  |  |  |  |
Drexel University | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Redeemable Common Stock |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Temporary equity new shares issued (in shares) | shares |  | 16,666 |  |  |  |  |  |
Tyligand | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Maximum obligation amount | $ 800,000 |  |  |  |  |  |  |
Quarterly sales payment due upon completion, percentage | 1.00% |  |  |  |  |  |  |
Quarterly sales payment due upon completion, period of payment | 15 years |  |  |  |  |  |  |
Number of securities called by warrants (in shares) | shares |  |  |  |  |  |  | 111,576 |
Warrant exercise price (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 7.17 |
Warrant fair value |  |  |  |  |  |  | $ 400,000 | $ 400,000
Research and development |  |  |  | 800,000 |  |  |  |
Integral | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Maximum obligation amount |  |  |  | $ 300,000 |  |  |  |
Maximum development and regulatory milestone payments |  |  | $ 55,300,000 |  |  |  |  |
Maximum sales milestone payments |  |  | $ 130,000,000 |  |  |  |  |
Tiered royalty payment, percent (up to) |  |  | 12.00% |  |  |  |  |
Integral | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Series A Preferred Stock |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Temporary equity, stock issued for services (in shares) | shares |  |  |  | 418,559 |  |  |  |
Temporary equity, stock issued for services |  |  |  | $ 2,800,000 |  |  |  |
Scale-up, 100 kilograms of GMP-grade compound | Tyligand | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Milestone payment | $ 2,000,000 |  |  |  |  |  |  |
Scale-up, 300 kilograms of GMP-grade compound | Tyligand | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |  |  |  |  |
Milestone payment | $ 3,000,000 |  |  |  |  |  |  |

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