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Share-Based Compensation - Additional Information (Details) - USD ($)
1 Months Ended 12 Months Ended
Apr. 30, 2021
Dec. 31, 2021
Dec. 31, 2020
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Annual rate at which authorized shares of common stock increase 4.00%    
Common stock, shares issued (in shares)     7,512
Weighted average fair value of grants during period (in dollars per share)   $ 3.84 $ 9.34
Granted during the period (in shares)   481,861 14,416
Aggregate intrinsic value of options outstanding and exercisable   $ 0  
Unrecognized compensation expense   $ 1,500,000  
Stock options      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based award contractual life   10 years  
Stock Granted For Services      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based compensation expense     $ 100,000
Minimum | Stock options      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based awards vesting period   1 year  
Maximum | Stock options      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based awards vesting period   4 years  
Common Stock      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Total shares of common stock authorized for issuance (in shares) 1,266,092    
Shares of common stock available for grant (in shares)   742,706  
Unvested restricted stock units      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Unrecognized expense related to RSUs   $ 0  
Unvested restricted stock units | Research and Development Expense      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based compensation expense   $ 33,000 2,000
Unvested restricted stock units | Minimum      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based awards vesting period   1 year  
Unvested restricted stock units | Maximum      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based awards vesting period   3 years  
Stock options      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected period for recognition   1 year 8 months 23 days  
Stock options | Research and Development Expense      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based compensation expense   $ 74,000 75,000
Stock options | General and Administrative Expense      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based compensation expense   $ 404,000 $ 29,000