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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
 3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Operating activities:    
Net loss $ (8,991,000) $ (7,837,000)
Adjustments to reconcile net loss to cash used in operating activities:    
Depreciation and amortization 17,000 8,000
Stock-based compensation 1,044,000 787,000
Net unrealized loss on foreign currency transactions 50,000 336,000
Non-cash consulting expense   81,000
Amortization of term loan discount and issuance costs 64,000 65,000
Realized gain on investments 0 (13,000)
Amortization/accretion of investments, net 100,000 (7,000)
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets 481,000 299,000
Accounts payable (489,000) (39,000)
Accrued expenses (220,000) (50,000)
Net cash used in operating activities (7,944,000) (6,370,000)
Investing activities:    
Purchases of property and equipment   (15,000)
Purchases of short-term investments (7,605,000) (2,225,000)
Maturities of short-term investments 12,465,000 15,245,000
Net cash provided by investing activities 4,860,000 13,005,000
Financing activities:    
Proceeds from registered direct offering, net of offering costs 29,960,000  
Proceeds from exercise of stock options 4,000  
Net cash provided by financing activities 29,964,000 775,000
Effect of exchange rate changes on cash and cash equivalents (1,000) (15,000)
Net increase in cash and cash equivalents 26,879,000 7,395,000
Cash and cash equivalents at beginning of period 23,982,000 13,219,000
Cash and cash equivalents at end of period 50,861,000 20,614,000
Supplemental disclosures of non-cash activities:    
Registered direct offering issuance costs in accounts payable $ 50,000  
ATM Facility    
Financing activities:    
Proceeds from issuance of common stock, net of issuance costs   775,000
Lincoln Park Capital Fund, LLC    
Supplemental disclosures of non-cash activities:    
Issuance of commitment shares to Lincoln Park pursuant to agreement   $ 171,000