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Partnerships - Additional Information (Details) ¥ in Billions | 1 Months Ended | 12 Months Ended | 31 Months Ended |  |
--- | --- | --- | --- | --- | ---
Dec. 31, 2022 USD ($) | May 31, 2017 USD ($) | Dec. 31, 2022 USD ($) | Nov. 30, 2019 shares | Mar. 16, 2023 USD ($) | Mar. 16, 2023 JPY (¥) | Dec. 05, 2022 USD ($) | Dec. 05, 2022 JPY (¥)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Deferred revenue current | $ 14,700,000 |  | $ 14,700,000 |  |  |  |  |
Deferred revenue long term | 10,378,000 |  | 10,378,000 |  |  |  |  |
Recognized revenue |  |  | 15,759,000 |  |  |  |  |
Ono | Asset Purchase Agreement |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Upfront non-refundable and non-creditable payment receivable, upon exchange of option |  |  |  |  |  |  | $ 26,400,000 | ¥ 3.5
Foreign curreny realized gain | 600,000 |  |  |  |  |  |  |
Upfront payment received | 26,400,000 |  |  |  |  |  |  |
Upfront non-refundable and non-creditable payment invoiced |  |  |  |  |  |  | 25,800,000 | ¥ 3.5
Upfront and non-creditable payment invoiced |  |  |  |  |  |  | 25,800,000 |
Estimated research and development funding |  |  |  |  |  |  | 76,800,000 |
Initial transaction price |  |  |  |  |  |  | 102,600,000 |
Deferred revenue | 25,100,000 |  | 25,100,000 |  |  |  | $ 25,800,000 |
Deferred revenue current | 14,700,000 |  | 14,700,000 |  |  |  |  |
Deferred revenue long term | 10,400,000 |  | 10,400,000 |  |  |  |  |
Proceeds from research and development fees | $ 12,200,000 |  |  |  |  |  |  |
Recognized revenue |  |  | $ 15,800,000 |  |  |  |  |
Option period expiry condition |  |  | he option period will expire three months following the delivery of topline data from the EQUALISE clinical study in lupus nephritis and interim data from the EQUATOR Phase 3 clinical study in acute graft-versus-host disease. |  |  |  |  |
Ono | Asset Purchase Agreement | Subsequent Event |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
One-time payment receivable, upon exercises the option |  |  |  |  | $ 37,200,000 | ¥ 5.0 |  |
Ono | Asset Purchase Agreement | Maximum | Subsequent Event |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Eligible to receive payment on achievement of certain development milestones |  |  |  |  | $ 101,400,000 |  |  |
Biocon |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Common stock shares issued | shares |  |  |  | 2,316,134 |  |  |  |
Biocon | Collaboration and License Agreement |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Regulatory milestone payments |  | $ 30,000,000 |  |  |  |  |  |
Sales milestone payments |  | $ 565,000,000 |  |  |  |  |  |
Research and Development Services | Ono | Asset Purchase Agreement |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Recognized revenue |  |  | $ 11,800,000 |  |  |  |  |
Upfront Payment Amortization | Ono | Asset Purchase Agreement |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Recognized revenue |  |  | $ 4,000,000.0 |  |  |  |  |

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