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Partnerships - Additional Information (Details) ¥ in Billions	1 Months Ended		3 Months Ended	31 Months Ended
	Dec. 31, 2022 USD ($)	May 31, 2017 USD ($)	Mar. 31, 2023 USD ($)	Nov. 30, 2019 shares	Mar. 16, 2023 USD ($)	Mar. 16, 2023 JPY (¥)	Dec. 05, 2022 USD ($)	Dec. 05, 2022 JPY (¥)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Deferred revenue current	$ 14,700,000		$ 14,767,000
Deferred revenue long term	10,378,000		7,941,000
Recognized revenue			8,879,000
Ono | Asset Purchase Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
One-time payment receivable, upon exercises the option					$ 37,200,000	¥ 5.0
Upfront non-refundable and non-creditable payment receivable, upon exchange of option							$ 26,400,000	¥ 3.5
Foreign curreny realized gain	600,000
Upfront payment received	$ 26,400,000
Upfront non-refundable and non-creditable payment invoiced							25,800,000	¥ 3.5
Upfront and non-creditable payment invoiced							25,800,000
Estimated research and development funding							76,800,000
Initial transaction price							102,600,000
Deferred revenue			22,700,000				$ 25,800,000
Deferred revenue current			14,800,000
Deferred revenue long term			7,900,000
Proceeds from research and development fees			18,100,000
Recognized revenue			$ 8,900,000
Option period expiry condition			the option period will expire three months following the delivery of topline data from the EQUALISE clinical study in lupus nephritis and interim data from the EQUATOR Phase 3 clinical study in acute graft-versus-host disease.
Ono | Asset Purchase Agreement | Maximum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Eligible to receive payment on achievement of certain development milestones					$ 101,400,000
Biocon
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Common stock shares issued | shares				2,316,134
Biocon | Collaboration and License Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Regulatory milestone payments		$ 30,000,000
Sales milestone payments		$ 565,000,000
Research and Development Services | Ono | Asset Purchase Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Recognized revenue			$ 6,700,000
Upfront Payment Amortization | Ono | Asset Purchase Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Recognized revenue			$ 2,200,000

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