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CONSOLIDATED STATEMENT OF CASH FLOWS - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Cash flows from operating activities    
Net loss $ (34,115) $ (44,256)
Adjustments to reconcile net loss to net cash (used in) provided by operating activities    
Depreciation expense 544 300
Stock-based compensation 5,177 1,797
Non-cash research and development expense for in-process research and development acquired in acquisition   11,140
Non-cash lease expense 1,174 964
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (1,452) 297
Accounts payable 361 519
Accrued expenses and other current liabilities 1,298 1,585
Lease liability (740) (978)
Deferred revenue (30,985) (9,194)
Deposits and other assets (1,514)  
Net cash flows used in operating activities (60,252) (37,826)
Cash flows from investing activities    
Cash obtained in asset acquisition   3,688
Payments to acquire property and equipment (1,760) (766)
Net cash flows (used in) provided by investing activities (1,760) 2,922
Cash flows from financing activities    
Proceeds from issuance of preferred stock, net of offering costs (146) 116,171
Proceeds from initial public offering, net of offering costs 131,302 (57)
Proceeds from exercise of stock options 582 70
Net cash flows provided by financing activities 131,738 116,184
Net increase in cash and cash equivalents 69,726 81,280
Cash, cash equivalents and restricted cash, beginning of year 163,363 82,083
Cash, cash equivalents and restricted cash, end of year 233,089 163,363
Cash and cash equivalents 232,217 162,491
Restricted cash included in other assets 872 872
Cash, cash equivalents and restricted cash, end of year 233,089 163,363
Supplemental disclosure of non-cash activities    
Assets obtained in asset acquisition   34
Liabilities assumed in asset acquisition   970
Fair value of equity instruments issued in connection with asset acquisition   13,892
Purchases of property and equipment in accounts payable and accrued expenses 13 367
Deferred transaction costs in accounts payable and accrued liabilities   591
Right-of-use assets recognized upon adoption of ASC 842   $ 956
Right-of-use assets and lease liabilities recognized upon lease inception $ 7,541