    <SEC-DOCUMENT>0001140361-25-014758-index.html : 20250421
    <SEC-HEADER>0001140361-25-014758.hdr.sgml : 20250421
    <ACCEPTANCE-DATETIME>20250421164229
    ACCESSION NUMBER:		0001140361-25-014758
    CONFORMED SUBMISSION TYPE:	S-4/A
    PUBLIC DOCUMENT COUNT:		41
    FILED AS OF DATE:		20250421
    DATE AS OF CHANGE:		20250421

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Ikena Oncology, Inc.
    		CENTRAL INDEX KEY:			0001835579
    		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				000000000
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		S-4/A
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-285881
    		FILM NUMBER:		25853884

    	BUSINESS ADDRESS:
    		STREET 1:		50 NORTHERN AVE.
    		CITY:			BOSTON
    		STATE:			MA
    		ZIP:			02210
    		BUSINESS PHONE:		857-343-8292

    	MAIL ADDRESS:
    		STREET 1:		50 NORTHERN AVE.
    		CITY:			BOSTON
    		STATE:			MA
    		ZIP:			02210
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>S-4/A
    <SEQUENCE>1
    <FILENAME>ny20041067x2_s4a.htm
    <DESCRIPTION>S-4/A
    <TEXT>
    Document 1 - file: ny20041067x2_s4a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.12
    <SEQUENCE>2
    <FILENAME>ny20041067x2_ex10-12.htm
    <DESCRIPTION>EXHIBIT 10.12
    <TEXT>
    Document 2 - file: ny20041067x2_ex10-12.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-23.1
    <SEQUENCE>3
    <FILENAME>ny20041067x2_ex23-1.htm
    <DESCRIPTION>EXHIBIT 23.1
    <TEXT>
    Document 3 - file: ny20041067x2_ex23-1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-23.2
    <SEQUENCE>4
    <FILENAME>ny20041067x2_ex23-2.htm
    <DESCRIPTION>EXHIBIT 23.2
    <TEXT>
    Document 4 - file: ny20041067x2_ex23-2.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.1
    <SEQUENCE>5
    <FILENAME>ny20041067x2_ex99-2.htm
    <DESCRIPTION>EXHIBIT 99.2
    <TEXT>
    Document 5 - file: ny20041067x2_ex99-2.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>logo_campbells.jpg
    <TEXT>
    Document 6 - file: logo_campbells.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>logo_ikena.jpg
    <TEXT>
    Document 7 - file: logo_ikena.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>logo_inmagene.jpg
    <TEXT>
    Document 8 - file: logo_inmagene.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>logo_leerink01.jpg
    <TEXT>
    Document 9 - file: logo_leerink01.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>ny20041067x2_barchart01.jpg
    <TEXT>
    Document 10 - file: ny20041067x2_barchart01.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>ny20041067x2_figure1.jpg
    <TEXT>
    Document 11 - file: ny20041067x2_figure1.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>ny20041067x2_figure2.jpg
    <TEXT>
    Document 12 - file: ny20041067x2_figure2.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>ny20041067x2_figure3.jpg
    <TEXT>
    Document 13 - file: ny20041067x2_figure3.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>ny20041067x2_figure4.jpg
    <TEXT>
    Document 14 - file: ny20041067x2_figure4.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>ny20041067x2_figure5.jpg
    <TEXT>
    Document 15 - file: ny20041067x2_figure5.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>ny20041067x2_figure6.jpg
    <TEXT>
    Document 16 - file: ny20041067x2_figure6.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>ny20041067x2_figure7.jpg
    <TEXT>
    Document 17 - file: ny20041067x2_figure7.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>ny20041067x2_figure8.jpg
    <TEXT>
    Document 18 - file: ny20041067x2_figure8.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>19
    <FILENAME>ny20041067x2_figure9a.jpg
    <TEXT>
    Document 19 - file: ny20041067x2_figure9a.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>20
    <FILENAME>ny20041067x2_figure9b.jpg
    <TEXT>
    Document 20 - file: ny20041067x2_figure9b.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>21
    <FILENAME>ny20041067x2_figure10.jpg
    <TEXT>
    Document 21 - file: ny20041067x2_figure10.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>22
    <FILENAME>ny20041067x2_figure11.jpg
    <TEXT>
    Document 22 - file: ny20041067x2_figure11.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>23
    <FILENAME>ny20041067x2_figure14.jpg
    <TEXT>
    Document 23 - file: ny20041067x2_figure14.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>24
    <FILENAME>ny20041067x2_figure15.jpg
    <TEXT>
    Document 24 - file: ny20041067x2_figure15.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>25
    <FILENAME>ny20041067x2_figure16.jpg
    <TEXT>
    Document 25 - file: ny20041067x2_figure16.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>26
    <FILENAME>ny20041067x2_flowchart01.jpg
    <TEXT>
    Document 26 - file: ny20041067x2_flowchart01.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>27
    <FILENAME>ny20041067x2_graphic01.jpg
    <TEXT>
    Document 27 - file: ny20041067x2_graphic01.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>28
    <FILENAME>ny20041067x2_graphic02.jpg
    <TEXT>
    Document 28 - file: ny20041067x2_graphic02.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>29
    <FILENAME>ny20041067x2_img418b.jpg
    <TEXT>
    Document 29 - file: ny20041067x2_img418b.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>30
    <FILENAME>ny20041067x2_img418c.jpg
    <TEXT>
    Document 30 - file: ny20041067x2_img418c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>31
    <FILENAME>ny20041067x2_img418d.jpg
    <TEXT>
    Document 31 - file: ny20041067x2_img418d.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>32
    <FILENAME>ny20041067x2_img418fx1.jpg
    <TEXT>
    Document 32 - file: ny20041067x2_img418fx1.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>33
    <FILENAME>ny20041067x2_img418x.jpg
    <TEXT>
    Document 33 - file: ny20041067x2_img418x.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>34
    <FILENAME>ny20041067x2_img418yx1.jpg
    <TEXT>
    Document 34 - file: ny20041067x2_img418yx1.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>35
    <FILENAME>ny20041067x2_img418z.jpg
    <TEXT>
    Document 35 - file: ny20041067x2_img418z.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>36
    <FILENAME>ny20041067x2_pc01.jpg
    <TEXT>
    Document 36 - file: ny20041067x2_pc01.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>37
    <FILENAME>ny20041067x2_pc02.jpg
    <TEXT>
    Document 37 - file: ny20041067x2_pc02.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>38
    <FILENAME>ny20041067x2_table3.jpg
    <TEXT>
    Document 38 - file: ny20041067x2_table3.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>39
    <FILENAME>ny20041067x2_table4.jpg
    <TEXT>
    Document 39 - file: ny20041067x2_table4.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>40
    <FILENAME>ny20041067x2_table6.jpg
    <TEXT>
    Document 40 - file: ny20041067x2_table6.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>41
    <FILENAME>ny20041067x2_table7.jpg
    <TEXT>
    Document 41 - file: ny20041067x2_table7.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>