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Related Party Transactions - Additional Information (Details) - USD ($)			3 Months Ended		6 Months Ended
	Apr. 14, 2026	Jul. 25, 2025	Jun. 30, 2026	Jun. 30, 2025	Jun. 30, 2026	Jun. 30, 2025	Dec. 31, 2025
Related Party Transaction [Line Items]
Research and development expense			$ 6,669,000	$ 5,653,000	$ 12,630,000	$ 9,693,000
Total general and administrative expense			5,115,000	$ 1,705,000	11,233,000	$ 4,460,000
Reimbursement of research and development expenses, received					600,000
Prepaid expenses and other current assets			4,959,000		4,959,000		$ 4,939,000
Maximum
Related Party Transaction [Line Items]
Reimbursement of research and development expenses			100,000		100,000
Transition Services Agreement | Miragene
Related Party Transaction [Line Items]
Research and development expense			100,000		300,000
Total general and administrative expense					100,000
Service agreement amount paid					200,000
Prepaid expenses							200,000
Transition Services Agreement | Maximum | Miragene
Related Party Transaction [Line Items]
Total general and administrative expense			100,000
Prepaid expenses			100,000		100,000
Promissory Note | Non-OX40 Divestiture
Related Party Transaction [Line Items]
Note receivable value		$ 8,900,000	$ 8,900,000		8,900,000
Proceeds from interest received					$ 0
Potential milestone license proceeds used to pay note receivable percentage					50.00%
Promissory Note | Non-OX40 Divestiture | Maximum
Related Party Transaction [Line Items]
Note receivable maturity year					2035
Promissory Note | Non-OX40 Divestiture | Interest Receivable
Related Party Transaction [Line Items]
Promissory note accrues interest at annual rate			4.61%		4.61%
Voting Common Stock | Pre-funded Warrants | 2026 Private Placement
Related Party Transaction [Line Items]
Warrants issued and sold to purchase warrant shares	5,770,335
Purchase price of warrants	$ 5.199
Gross proceeds from issuance of warrants	$ 30,000,000
Extension Term | Transition Services Agreement | Miragene
Related Party Transaction [Line Items]
Service agreement term		6 months
Initial Term Period | Transition Services Agreement | Miragene
Related Party Transaction [Line Items]
Service agreement term		6 months
Related Party | Accounts Receivable
Related Party Transaction [Line Items]
Prepaid expenses and other current assets							$ 500,000
Affiliated Entity | 2026 Private Placement | Minimum
Related Party Transaction [Line Items]
Percentage of stockholders owning company's sotck	5.00%
Affiliated Entity | Voting Common Stock | Pre-funded Warrants | 2026 Private Placement
Related Party Transaction [Line Items]
Purchase price of warrants	$ 5.199
Gross proceeds from issuance of warrants	$ 11,500,000
Affiliated Entity | Voting Common Stock | Pre-funded Warrants | 2026 Private Placement | Maximum
Related Party Transaction [Line Items]
Warrants issued and sold to purchase warrant shares	2,211,961

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