v3.19.2

Stock-Based Compensation (Tables)

6 Months Ended

Jun. 30, 2019

Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]

Summary of Stock Option Activity

The following table summarizes the stock option activity during the six months ended June 30, 2019:

		Stock Option Shares				Weighted Average Exercise Price				Weighted Average Remaining Contractual Term (in Years)				Aggregate Intrinsic Value
Outstanding, January 1, 2019			3,351,132			$	3.73				8.24			$	142,788
Granted			4,622,428				1.86
Exercised			—				—
Expired/cancelled			(1,201,753	)			2.80
Outstanding, June 30, 2019			6,771,807			$	2.62				8.65			$	17,133
Expected to vest, June 30, 2019			5,183,231			$	2.37			9.35				$	—
Options exercisable, June 30, 2019			1,588,576			$	3.43				6.37			$	17,133

Summary of Recognized Compensation Cost Related to Employee and Non-employee Stock-Based Compensation Activity

The Company recognized the following compensation cost related to employee and non-employee stock-based compensation activity:

		Three Months Ended June 30,								Six Months Ended June 30,
		2019				2018				2019				2018
Research and development		$	73,463			$	114,949			$	232,794			$	174,013
General and administrative			531,198				762,808				993,552				1,783,465
Total		$	604,661			$	877,757			$	1,226,346			$	1,957,478

Stock Options Valuation Assumptions

The calculation was based on the following assumptions.

		Three Months Ended			Six Months Ended
		June 30, 2019			June 30, 2019
Expected term (years)		5.82			5.77
Risk-free interest rate		2.21%			2.32%
Expected volatility		65.97%			65.83%
Expected dividend yield		0.00%			0.00%

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Tabular disclosure of the allocation of equity-based compensation costs to a given line item on the balance sheet and income statement for the period. This may include the reporting line for the costs and the amount capitalized and expensed.

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Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

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Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

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