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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (USD $) | 12 Months Ended
--- | ---
Dec. 31, 2012 | Dec. 31, 2011 | Dec. 31, 2010
Product revenues: |  |  |
Related party | $ 0 | $ 0 | $ 590,000
Third party | 8,709,000 | 7,983,000 | 7,664,000
Total product revenues | 8,709,000 | 7,983,000 | 8,254,000
Cost of product revenues | 4,000,000 | 3,837,000 | 3,908,000
Gross profit | 4,709,000 | 4,146,000 | 4,346,000
Development revenues: |  |  |
Development, related party | 2,882,000 | 1,992,000 | 2,122,000
Development | 2,529,000 | 0 | 0
Government contracts and other | 381,000 | 21,000 | 251,000
Total development revenues | 5,792,000 | 2,013,000 | 2,373,000
Operating expenses: |  |  |
Research and development | 13,628,000 | 10,904,000 | 9,687,000
Sales and marketing | 9,488,000 | 13,560,000 | 11,040,000
General and administrative | 15,672,000 | 14,727,000 | 12,570,000
Change in fair value of warrants | (209,000) | (4,360,000) | (1,285,000)
Change in fair value of option liability | 340,000 | 740,000 | 30,000
Total operating expenses | 38,919,000 | 35,571,000 | 32,042,000
Operating income (loss) | (28,418,000) | (29,412,000) | (25,323,000)
Other income (expense): |  |  |
Interest income | 4,000 | 9,000 | 9,000
Interest expense | (3,386,000) | (2,784,000) | (2,052,000)
Other income (expense), net | (314,000) | (55,000) | 23,000
Equity loss from investment in joint venture | (165,000) | (209,000) | (151,000)
Total other income (expense) | (3,861,000) | (3,039,000) | (2,171,000)
Net loss | $ (32,279,000) | $ (32,451,000) | $ (27,494,000)
Basic and diluted net loss per common share (in dollars per share) | $ (0.55) | $ (0.61) | $ (0.6)
Basic and diluted weighted average common shares (in shares) | 58,679,687 | 53,504,030 | 45,947,966

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