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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (DEFICIT) (USD $) | Common Stock [Member] | Additional Paid-in Capital [Member] | Accumulated Deficit [Member] | Total
--- | --- | --- | --- | ---
Balance at period beginning at Dec. 31, 2009 | $ 40,000 | $ 178,806,000 | $ (182,504,000) | $ (3,658,000)
Balance at period beginning (in shares) at Dec. 31, 2009 | 40,039,259 |  |  |
Stock-based compensation expense | 0 | 3,055,000 | 0 | 3,055,000
Issuance of common stock under stock option plan (in shares) | 378,705 |  |  |
Issuance of common stock under stock option plan | 0 | 1,393,000 | 0 | 1,393,000
Issuance of common stock under stock warrant agreement (in shares) | 2,208,730 |  |  |
Issuance of common stock under stock warrant agreement | 2,000 | 5,733,000 | 0 | 5,735,000
Sale of common stock, net (in shares) | 9,328,571 |  |  |
Sale of common stock, net | 10,000 | 43,553,000 | 0 | 43,563,000
Allocation of fair value for debt-related warrants | 0 | 279,000 | 0 | 279,000
Net loss | 0 | 0 | (27,494,000) | (27,494,000)
Balance at period end at Dec. 31, 2010 | 52,000 | 232,819,000 | (209,998,000) | 22,873,000
Balance at period end (in shares) at Dec. 31, 2010 | 51,955,265 |  |  |
Stock-based compensation expense | 0 | 3,316,000 | 0 | 3,316,000
Issuance of common stock under stock option plan (in shares) | 222,283 |  |  |
Issuance of common stock under stock option plan | 0 | 767,000 | 0 | 767,000
Issuance of common stock under stock warrant agreement (in shares) | 340,873 |  |  |
Issuance of common stock under stock warrant agreement | 1,000 | 2,081,000 | 0 | 2,082,000
Sale of common stock, net (in shares) | 4,076,262 |  |  |
Sale of common stock, net | 4,000 | 13,088,000 | 0 | 13,092,000
Allocation of fair value for debt-related warrants | 0 | 267,000 | 0 | 267,000
Net loss | 0 | 0 | (32,451,000) | (32,451,000)
Balance at period end at Dec. 31, 2011 | 57,000 | 252,338,000 | (242,449,000) | 9,946,000
Balance at period end (in shares) at Dec. 31, 2011 | 56,594,683 |  |  | 56,594,683
Stock-based compensation expense | 0 | 3,904,000 | 0 | 3,904,000
Issuance of common stock under stock option plan (in shares) | 450,512 |  |  |
Issuance of common stock under stock option plan | 0 | 1,157,000 | 0 | 1,157,000
Issuance of common stock under stock warrant agreement (in shares) | 98,855 |  |  |
Issuance of common stock under stock warrant agreement | 0 | 256,000 | 0 | 256,000
Sale of common stock, net (in shares) | 8,770,000 |  |  |
Sale of common stock, net | 9,000 | 23,462,000 | 0 | 23,471,000
Net loss | 0 | 0 | (32,279,000) | (32,279,000)
Balance at period end at Dec. 31, 2012 | $ 66,000 | $ 281,117,000 | $ (274,728,000) | $ 6,455,000
Balance at period end (in shares) at Dec. 31, 2012 | 65,914,050 |  |  | 65,914,050

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