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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (DEFICIT) (USD $)
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Deficit [Member]
Total
Balance at period beginning at Dec. 31, 2009 $ 40,000 $ 178,806,000 $ (182,504,000) $ (3,658,000)
Balance at period beginning (in shares) at Dec. 31, 2009 40,039,259      
Stock-based compensation expense 0 3,055,000 0 3,055,000
Issuance of common stock under stock option plan (in shares) 378,705      
Issuance of common stock under stock option plan 0 1,393,000 0 1,393,000
Issuance of common stock under stock warrant agreement (in shares) 2,208,730      
Issuance of common stock under stock warrant agreement 2,000 5,733,000 0 5,735,000
Sale of common stock, net (in shares) 9,328,571      
Sale of common stock, net 10,000 43,553,000 0 43,563,000
Allocation of fair value for debt-related warrants 0 279,000 0 279,000
Net loss 0 0 (27,494,000) (27,494,000)
Balance at period end at Dec. 31, 2010 52,000 232,819,000 (209,998,000) 22,873,000
Balance at period end (in shares) at Dec. 31, 2010 51,955,265      
Stock-based compensation expense 0 3,316,000 0 3,316,000
Issuance of common stock under stock option plan (in shares) 222,283      
Issuance of common stock under stock option plan 0 767,000 0 767,000
Issuance of common stock under stock warrant agreement (in shares) 340,873      
Issuance of common stock under stock warrant agreement 1,000 2,081,000 0 2,082,000
Sale of common stock, net (in shares) 4,076,262      
Sale of common stock, net 4,000 13,088,000 0 13,092,000
Allocation of fair value for debt-related warrants 0 267,000 0 267,000
Net loss 0 0 (32,451,000) (32,451,000)
Balance at period end at Dec. 31, 2011 57,000 252,338,000 (242,449,000) 9,946,000
Balance at period end (in shares) at Dec. 31, 2011 56,594,683     56,594,683
Stock-based compensation expense 0 3,904,000 0 3,904,000
Issuance of common stock under stock option plan (in shares) 450,512      
Issuance of common stock under stock option plan 0 1,157,000 0 1,157,000
Issuance of common stock under stock warrant agreement (in shares) 98,855      
Issuance of common stock under stock warrant agreement 0 256,000 0 256,000
Sale of common stock, net (in shares) 8,770,000      
Sale of common stock, net 9,000 23,462,000 0 23,471,000
Net loss 0 0 (32,279,000) (32,279,000)
Balance at period end at Dec. 31, 2012 $ 66,000 $ 281,117,000 $ (274,728,000) $ 6,455,000
Balance at period end (in shares) at Dec. 31, 2012 65,914,050     65,914,050