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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (USD $)
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Deficit [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Total
Balance at period beginning at Dec. 31, 2010 $ 52,000 $ 232,819,000 $ (209,998,000)   $ 22,873,000
Balance at period beginning (in shares) at Dec. 31, 2010 51,955,265        
Stock-based compensation expense 0 3,316,000 0   3,316,000
Issuance of common stock under stock option plan and employee stock purchase plan (in shares) 222,283        
Issuance of common stock under stock option plan and employee stock purchase plan 0 767,000 0   767,000
Issuance of common stock under stock warrant agreement (in shares) 340,873        
Issuance of common stock under stock warrant agreement 1,000 2,081,000 0   2,082,000
Sale of common stock, net (in shares) 4,076,262        
Sale of common stock, net 4,000 13,088,000 0   13,092,000
Allocation of fair value for debt-related warrants 0 267,000 0   267,000
Net loss 0 0 (32,451,000)   (32,451,000)
Balance at period end at Dec. 31, 2011 57,000 252,338,000 (242,449,000)   9,946,000
Balance at period end (in shares) at Dec. 31, 2011 56,594,683        
Stock-based compensation expense 0 3,904,000 0   3,904,000
Issuance of common stock under stock option plan and employee stock purchase plan (in shares) 450,512        
Issuance of common stock under stock option plan and employee stock purchase plan 0 1,157,000 0   1,157,000
Issuance of common stock under stock warrant agreement (in shares) 98,855        
Issuance of common stock under stock warrant agreement 0 256,000 0   256,000
Sale of common stock, net (in shares) 8,770,000        
Sale of common stock, net 9,000 23,462,000 0   23,471,000
Net loss 0 0 (32,279,000)   (32,279,000)
Balance at period end at Dec. 31, 2012 66,000 281,117,000 (274,728,000) 0 6,455,000
Balance at period end (in shares) at Dec. 31, 2012 65,914,050       65,914,050
Stock-based compensation expense 0 3,608,000 0   3,608,000
Issuance of common stock under stock option plan and employee stock purchase plan (in shares) 338,325        
Issuance of common stock under stock option plan and employee stock purchase plan 0 225,000 0   225,000
Sale of common stock, net (in shares) 5,053,000        
Sale of common stock, net 5,000 17,811,000 0   17,816,000
Allocation of fair value for debt-related warrants   949,000     949,000
Accumulated other comprehensive income (loss)       256,000 256,000
Net loss 0 0 (26,177,000)   (26,177,000)
Balance at period end at Dec. 31, 2013 $ 71,000 $ 303,710,000 $ (300,905,000) $ 256,000 $ 3,132,000
Balance at period end (in shares) at Dec. 31, 2013 71,305,375       71,305,375