Quarterly Information (unaudited) (Tables)

12 Months Ended

Dec. 31, 2014

Quarterly Information (unaudited) [Abstract]

Unaudited Quarterly Financial Information

The following unaudited quarterly financial information includes, in management’s opinion, all the normal and recurring adjustments necessary to fairly state the results of operations and related information for the periods presented:

	For the three months ended
	March 31, 2014			June 30, 2014			September 30, 2014			December 31, 2014

Product revenues	$	1,031,000		$	935,000		$	518,000		$	2,469,000
Gross profit		610,000			169,000			181,000			1,053,000
Development revenues		403,000			356,000			585,000			1,301,000
Operating expenses		(10,560,000	)		(11,210,000	)		(8,656,000	)		(6,669,000	)
Other income (expense)		(853,000	)		(1,143,000	)		(1,495,000	)		(1,440,000	)
Net loss	$	(10,400,000	)	$	(11,828,000	)	$	(9,385,000	)	$	(5,755,000	)
Beneficial conversion feature for convertible preferred stock		—			—			—			(1,169,000	)
Net loss allocable to common stock holders…		(10,400,000	)		(11,828,000	)		(9,385,000	)		(6,924,000	)
Basic and diluted net loss per share	$	(0.14	)	$	(0.15	)	$	(0.12	)	$	(0.08	)

	For the three months ended
	March 31, 2013			June 30, 2013			September 30, 2013			December 31, 2013

Product revenues	$	1,392,000		$	1,408,000		$	1,616,000		$	2,706,000
Gross profit		636,000			800,000			685,000			1,580,000
Development revenues		2,366,000			859,000			1,095,000			754,000
Operating expenses		(9,739,000	)		(8,022,000	)		(10,241,000	)		(11,452,000	)
Other income (expense)		(930,000	)		3,152,000			3,203,000			(923,000	)
Net loss	$	(7,667,000	)	$	(3,211,000	)	$	(5,258,000	)	$	(10,041,000	)
Basic and diluted net loss per share	$	(0.11	)	$	(0.05	)	$	(0.08	)	$	(0.14	)