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Quarterly Information (unaudited) (Details) - USD ($) | 3 Months Ended | 12 Months Ended
--- | --- | ---
Dec. 31, 2015 | Sep. 30, 2015 | Jun. 30, 2015 | Mar. 31, 2015 | Dec. 31, 2014 | Sep. 30, 2014 | Jun. 30, 2014 | Mar. 31, 2014 | Dec. 31, 2015 | Dec. 31, 2014 | Dec. 31, 2013
Quarterly Information (unaudited) [Abstract] |  |  |  |  |  |  |  |  |  |  |
Product revenues | $ 1,556,000 | $ 766,000 | $ 1,614,000 | $ 902,000 | $ 2,469,000 | $ 518,000 | $ 935,000 | $ 1,031,000 | $ 4,838,000 | $ 4,953,000 | $ 7,122,000
Gross profit | 765,000 | 264,000 | 318,000 | 305,000 | 1,053,000 | 181,000 | 169,000 | 610,000 | 1,652,000 | 2,013,000 | 3,701,000
Development revenues | 1,820,000 | 1,710,000 | 1,847,000 | 1,444,000 | 1,301,000 | 585,000 | 356,000 | 403,000 | 6,821,000 | 2,645,000 | 5,074,000
Operating expenses | (4,656,000) | 16,000 | 3,626,000 | (22,745,000) | (6,669,000) | (8,656,000) | (11,210,000) | (10,560,000) | 23,759,000 | 37,095,000 | 39,454,000
Other income (expense) | (685,000) | (470,000) | (1,342,000) | (961,000) | (1,440,000) | (1,495,000) | (1,143,000) | (853,000) | (3,458,000) | (4,931,000) | 4,502,000
Net loss for the year ended | (2,756,000) | 1,520,000 | 4,449,000 | (21,957,000) | (5,755,000) | (9,385,000) | (11,828,000) | (10,400,000) | (18,744,000) | (37,368,000) | (26,177,000)
Beneficial conversion feature for convertible preferred stock | 0 | 0 | 0 | (661,000) | (1,169,000) | 0 | 0 | 0 | (661,000) | (1,169,000) | 0
Net income (loss) allocable to common stock holders | $ (2,756,000) | $ 1,520,000 | $ 4,449,000 | $ (22,618,000) | $ (6,924,000) | $ (9,385,000) | $ (11,828,000) | $ (10,400,000) | $ (19,405,000) | $ (38,537,000) | $ (26,177,000)
Basic and diluted net loss per share (in dollars per share) | $ (0.02) | $ 0.01 | $ 0.03 | $ (0.21) | $ (0.08) | $ (0.12) | $ (0.15) | $ (0.14) | $ (0.14) | $ (0.48) | $ (0.39)

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- Definition Aggregate revenue earned during the period from recognition of related party deferred revenue, non-product related activities and revenue earned during the period from non-repayable sum of money awarded to an entity to carry out a specific purpose as provided in grant agreements. + References No definition available. + Details
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