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Income Taxes (Details) - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2015 | Dec. 31, 2014 | Dec. 31, 2013
Reconciliation of the total income tax provision tax rate [Abstract] |  |  |
Income tax expense (benefit) at federal statutory rate | (34.00%) | (34.00%) | (34.00%)
Income tax expense (benefit) at state statutory rate | (4.40%) | (3.52%) | (3.54%)
Gain on previously held equity interest in joint venture | 0.00% | 0.00% | (7.02%)
Mark to market permanent adjustment | (13.91%) | (0.37%) | (2.15%)
Change in valuation allowance | (7.45%) | 27.12% | 80.13%
Change in state rate | (0.09%) | 0.02% | (1.01%)
Permanent interest adjustments | 6.25% | 4.17% | 0.00%
Stock compensation | 20.43% | 0.00% | 0.00%
Transfer pricing | 18.49% | 0.00% | 0.00%
Debt refinance permanent adjustment | 0.00% | 3.92% | 0.00%
Acquired NOL's/Intangibles from joint venture | 0.00% | 0.00% | (33.40%)
Research credit | (2.37%) | (0.74%) | (3.75%)
Foreign rate differential | 0.69% | 0.00% | 2.48%
NOLs expiring | 13.92% | 0.00% | 0.00%
Other, net | 2.44% | 3.40% | 2.26%
Total income tax provision | 0.00% | 0.00% | 0.00%
Deferred tax assets [Abstract] |  |  |
Allowances and reserves | $ 673,000 | $ 825,000 |
Accrued expenses | 951,000 | 502,000 |
Deferred revenue and gain-on-sale | 39,000 | 32,000 |
Stock based compensation | 4,547,000 | 7,786,000 |
Net operating loss carryforwards | 119,000,000 | 117,258,000 |
Income tax credit carryforwards | 7,437,000 | 6,993,000 |
Property and equipment, principally due to differences in depreciation | 683,000 | 926,000 |
Other, net | 16,000 | 77,000 |
Deferred tax assets (Total) | 133,346,000 | 134,399,000 |
Valuation allowance | (131,187,000) | (132,583,000) |
Total deferred tax assets, net of allowance | 2,159,000 | 1,816,000 |
Deferred tax liabilities [Abstract] |  |  |
Intangibles | (2,159,000) | (1,816,000) |
Total deferred tax liability | (2,159,000) | (1,816,000) |
Net deferred tax assets (liability) | 0 | 0 |
Schedule of reconciliation of unrecognized tax benefits activity [Roll Forward] |  |  |
Unrecognized Tax Benefits - Beginning | 1,852,000 | 1,723,000 | $ 1,394,000
Gross increases - tax positions in prior period | 0 | 0 | 69,000
Gross decreases - tax positions in prior period | 0 | 0 | 0
Gross increase - current-period tax positions | 135,000 | 129,000 | 260,000
Settlements | 0 | 0 | 0
Lapse of statute of limitations | 0 | 0 | 0
Unrecognized Tax Benefits - Ending | 1,987,000 | $ 1,852,000 | $ 1,723,000
Income Tax Contingency [Line Items] |  |  |
Decrease in valuation allowance | $ (1,396,000) |  |
Net operating loss carryforwards, Expire date | Begin to expire in 2019 and 2016 |  |
State tax credit carryforwards | $ 4,271,000 |  |
Cumulative change in ownership | 50.00% |  |
Period of net operating loss and R&D tax credit carry forwards to offset future taxable income | 3 years |  |
Excess tax benefits | $ 1,265,000 |  |
Period for material changes of liability for uncertain tax benefits | 12 months |  |
Federal [Member] |  |  |
Income Tax Contingency [Line Items] |  |  |
Tax loss carryforwards | $ 323,938,000 |  |
Federal tax carry forward | $ 4,618,000 |  |
Federal tax credit carryforward, Expiration date | Begin to expire in 2018 |  |
California [Member] |  |  |
Income Tax Contingency [Line Items] |  |  |
Tax loss carryforwards | $ 166,612,000 |  |

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