Quarterly Information (unaudited) (Tables)

12 Months Ended

Dec. 31, 2015

Quarterly Information (unaudited) [Abstract]

Unaudited Quarterly Financial Information

The following unaudited quarterly financial information includes, in management’s opinion, all the normal and recurring adjustments necessary to fairly state the results of operations and related information for the periods presented:

	For the three months ended
	March 31, 2015			June 30, 2015			September 30, 2015			December 31, 2015

Product revenues	$	902,000		$	1,614,000		$	766,000		$	1,556,000
Gross profit		305,000			318,000			264,000			765,000
Development revenues		1,444,000			1,847,000			1,710,000			1,820,000
Operating expenses		(22,745,000	)		3,626,000			16,000			(4,656,000	)
Other income (expense)		(961,000	)		(1,342,000	)		(470,000	)		(685,000	)
Net income (loss)	$	(21,957,000	)	$	4,449,000		$	1,520,000		$	(2,756,000	)
Beneficial conversion feature for convertible preferred stock		(661,000	)		—			—			—
Net income (loss) allocable to common stock holders		(22,618,000	)		4,449,000			1,520,000			(2,756,000	)
Basic and diluted net loss per share	$	(0.21	)	$	0.03		$	0.01		$	(0.02	)

	For the three months ended
	March 31, 2014			June 30, 2014			September 30, 2014			December 31, 2014

Product revenues	$	1,031,000		$	935,000		$	518,000		$	2,469,000
Gross profit		610,000			169,000			181,000			1,053,000
Development revenues		403,000			356,000			585,000			1,301,000
Operating expenses		(10,560,000	)		(11,210,000	)		(8,656,000	)		(6,669,000	)
Other income (expense)		(853,000	)		(1,143,000	)		(1,495,000	)		(1,440,000	)
Net loss	$	(10,400,000	)	$	(11,828,000	)	$	(9,385,000	)	$	(5,755,000	)
Beneficial conversion feature for convertible preferred stock		—			—			—			(1,169,000	)
Net loss allocable to common stock holders		(10,400,000	)		(11,828,000	)		(9,385,000	)		(6,924,000	)
Basic and diluted net loss per share	$	(0.14	)	$	(0.15	)	$	(0.12	)	$	(0.08	)