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Liquidity (Details) - USD ($)
 3 Months Ended 9 Months Ended
Jun. 16, 2016
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Jun. 15, 2016
May 10, 2016
Mar. 31, 2016
Dec. 31, 2015
Liquidity [Line Items]                  
Net loss   $ (5,384,000) $ 1,527,000 $ (17,127,000) $ (15,981,000)        
Accumulated deficit   $ 374,144,000   374,144,000         $ 357,017,000
Net cash used in operating activities       $ 15,372,000 $ 15,946,000        
Common stock issued (in shares) 6,704,852                
Each unit consist of number of warrant 3,352,306                
Number of shares callable by warrants (in shares)           1 1,100,000 16,000,000  
Warrant exercise price (in dollars per share)           $ 3.06      
Proceeds from issuance warrants $ 17,100,000                
Common Stock [Member]                  
Liquidity [Line Items]                  
Common stock issued (in shares) 6,704,852     6,704,852          
Each unit consist of number of warrant       0.5          
Number of shares callable by warrants (in shares)   1   1          
Warrant exercise price (in dollars per share)   $ 3.06   $ 3.06