Quarterly Information (unaudited) (Tables)

12 Months Ended

Dec. 31, 2016

Quarterly Financial Information Disclosure [Abstract]

Unaudited Quarterly Financial Information

The following unaudited quarterly financial information includes, in management’s opinion, all the normal and recurring adjustments necessary to fairly state the results of operations and related information for the periods presented (in thousands):

	For the three months ended
	March 31, 2016			June 30, 2016			September 30, 2016			December 31, 2016
Product revenues	$	1,333		$	1,126		$	731		$	1,466
Gross profit		766			541			113			521
Development revenues		1,585			1,699			1,879			1,561
Operating expenses		(7,448	)		(8,464	)		(6,789	)		(5,670	)
Other expense, net		(242	)		(181	)		(587	)		(1,330	)
Net income (loss)	$	(5,339	)	$	(6,405	)	$	(5,384	)	$	(4,918	)
Beneficial conversion feature for convertible preferred stock		—			—			—			—
Net income (loss) allocable to common stock holders		(5,339	)		(6,405	)		(5,384	)		(4,918	)
Basic and diluted net loss per share	$	(0.41	)	$	(0.43	)	$	(0.26	)	$	(0.24	)

	For the three months ended
	March 31, 2015			June 30, 2015			September 30, 2015			December 31, 2015
Product revenues	$	902		$	1,614		$	766		$	1,556
Gross profit		305			318			264			765
Development revenues		1,444			1,847			1,710			1,820
Operating expenses		(22,745	)		3,626			16			(4,656	)
Other expense, net		(961	)		(1,342	)		(470	)		(685	)
Net income (loss)	$	(21,957	)	$	4,449		$	1,520		$	(2,756	)
Beneficial conversion feature for convertible preferred stock		(661	)		—			—			—
Net income (loss) allocable to common stock holders		(22,618	)		4,449			1,520			(2,756	)
Basic and diluted net loss per share	$	(3.19	)	$	0.45		$	0.15		$	(0.25	)