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Summary of Significant Accounting Policies - Additional Information (Details)
 1 Months Ended 12 Months Ended
May 31, 2015
USD ($)
Closing
$ / shares
shares
May 31, 2013
Dec. 31, 2016
USD ($)
Distributor
Customer
Segment
$ / shares
shares
Dec. 31, 2015
USD ($)
Distributor
Customer
Segment
shares
Jun. 15, 2016
$ / shares
shares
May 11, 2016
shares
May 10, 2016
shares
Dec. 17, 2015
USD ($)
shares
Aug. 31, 2015
USD ($)
Summary Of Significant Accounting Policies [Line Items]                  
Cash equivalents investments with original maturities     $ 0 $ 0          
Impairment loss     0 0          
Impairment of goodwill     0 0          
Acquired technology intangible assets     9,400,000            
Useful life (in years)   11 years              
Amortization expense     584,000 397,000          
2017     1,200,000            
2018     1,200,000            
Thereafter     6,000,000            
Accumulated amortization on intangible assets     1,200,000 600,000          
Exercise price per shares (in dollars per share) | $ / shares         $ 3.06        
Common stock issued, value     $ 19,478,000 $ 10,701,000          
Number of shares callable by warrants (in shares) | shares         1 1,100,000 16,000,000    
Period of services provided subsequent to date of sale     1 year            
Concentration risk percentage     100.00% 100.00%          
Total development revenues     $ 6,724,000 $ 6,821,000          
Qualifying expenditures related to research     6,300,000 6,300,000          
Interest or penalties related to income tax matters     $ 0 $ 0          
Number of operating segment | Segment     1 1          
Dilutive securities excluded from the calculations of diluted loss per share (in shares) | shares     4,200,000 12,300,000          
Options and Restricted Stock [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Dilutive securities excluded from the calculations of diluted loss per share (in shares) | shares     600,000            
BARDA Contract [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Total development revenues     $ 6,700,000 $ 6,800,000          
Customer Concentration Risk [Member] | Revenue Recognized [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Number of distributor | Distributor     2 1          
Number of customers | Customer     3 4          
Concentration risk percentage     65.00% 63.00%          
Customer Concentration Risk [Member] | Accounts Receivable [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Number of customers | Customer     2 2          
Concentration risk percentage     57.00% 73.00%          
Securities Purchase Agreement [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Common stock issued, value $ 25,000,000                
Number of closings | Closing 2                
Warrant [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Warrant liability     $ 10,000,000            
Dilutive securities excluded from the calculations of diluted loss per share (in shares) | shares     3,600,000            
Warrant [Member] | Securities Purchase Agreement [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Number of shares callable by warrants (in shares) | shares 1                
Common Stock [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Exercise price per shares (in dollars per share) | $ / shares     $ 3.06            
Period exercisable from the date of issuance     30 months            
Common stock issued, value     $ 9,000 $ 2,000          
Number of shares callable by warrants (in shares) | shares     1            
Common Stock [Member] | 2015 Amendment [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Number of shares callable by each warrant (in shares) | shares               0.75  
Common Stock [Member] | 2014 Amendment [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Number of shares callable by each warrant (in shares) | shares               0.69  
Common Stock [Member] | Securities Purchase Agreement [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Number of shares callable by warrants (in shares) | shares 1                
Number of shares callable by each warrant (in shares) | shares 1                
October 2014 warrants [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Exercise price per shares (in dollars per share) | $ / shares     $ 0.5771            
Period exercisable from the date of issuance     6 months 1 day            
Expiration term of warrant     5 years            
Warrant liability               $ 3,300,000  
October 2015 warrants [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Exercise price per shares (in dollars per share) | $ / shares $ 0.3263                
May 2015 Warrants [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Exercise price per shares (in dollars per share) | $ / shares $ 1.02                
Period exercisable from the date of issuance     6 months 1 day            
Expiration term of warrant     5 years            
Warrant liability $ 14,300,000             5,000,000  
August 2015 Warrants [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Exercise price per shares (in dollars per share) | $ / shares $ 0.401                
Expiration term of warrant     5 years            
Warrant liability               $ 1,500,000 $ 1,600,000
Minimum [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Useful lives of the assets     3 years            
Maximum [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Useful lives of the assets     5 years            
Letter of Credit [Member]                  
Summary Of Significant Accounting Policies [Line Items]                  
Letter of credit amount required by lease agreement     $ 400,000            
Restricted cash required to maintained under Lease agreement     $ 400,000            
Lease expiration date     Oct. 31, 2017