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Income Taxes - Additional Information (Details) - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2016
Income Taxes [Line Items] |  |  |
Provision or benefit for income taxes |  | $ 0 | $ 0
Income Tax Contingency [Abstract] |  |  |
Valuation allowance |  | 97,089,000 | $ 134,873,000
Increase (decrease) in valuation allowance |  | $ (37,800,000) |
Corporate income tax rate |  | 34.00% | 34.00%
Net operating loss carryforwards, Expire date |  | Begin to expire in 2019 and 2017 |
State tax credit carryforwards |  | $ 4,500,000 |
Cumulative change in ownership |  | 50.00% |
Period of net operating loss and R&D tax credit carry forwards to offset future taxable income |  | 3 years |
Increase in income tax rate |  | $ 45,800,000 |
Decrease in net deferred tax assets |  | (45,800,000) |
Liability for uncertain tax positions |  | $ 0 | $ 0
Period for material changes of liability for uncertain tax benefits |  | 12 months |
Maximum [Member] |  |  |
Income Tax Contingency [Abstract] |  |  |
Corporate income tax rate |  | 35.00% |
Scenario Plan [Member] |  |  |
Income Tax Contingency [Abstract] |  |  |
Corporate income tax rate | 21.00% |  |
Federal [Member] |  |  |
Income Tax Contingency [Abstract] |  |  |
Tax loss carryforwards |  | $ 365,900,000 |
Federal tax carry forward |  | $ 5,100,000 |
Federal tax credit carryforward, Expiration date |  | Begin to expire in 2018 |
State [Member] |  |  |
Income Tax Contingency [Abstract] |  |  |
Tax loss carryforwards |  | $ 147,400,000 |

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