Quarterly Information (unaudited) (Tables)

12 Months Ended

Dec. 31, 2017

Quarterly Financial Information Disclosure [Abstract]

Unaudited Quarterly Financial Information

The following unaudited quarterly financial information includes, in management’s opinion, all the normal and recurring adjustments necessary to fairly state the results of operations and related information for the periods presented (in thousands):

	For the three months ended
	March 31, 2017			June 30, 2017			September 30, 2017			December 31, 2017
Product revenues	$	591		$	969		$	467		$	662
Gross profit		(125	)		262			(20	)		29
Development revenues		1,018			531			1,306			867
Operating expenses		(6,336	)		(6,374	)		(5,629	)		(4,526	)
In process research and development acquired from Azaya		(1,686	)		—			—			—
Other expense, net		(415	)		(468	)		(464	)		(656	)
Net income (loss)	$	(7,544	)	$	(6,049	)	$	(4,807	)	$	(4,286	)
Beneficial conversion feature for convertible preferred stock		—			—			—			(3,977	)
Net income (loss) allocable to common stock holders		(7,544	)		(6,049	)		(4,807	)		(8,263	)
Basic and diluted net loss per share	$	(0.33	)	$	(0.19	)	$	(0.14	)	$	(0.20	)

	For the three months ended
	March 31, 2016			June 30, 2016			September 30, 2016			December 31, 2016
Product revenues	$	1,333		$	1,126		$	731		$	1,466
Gross profit		766			541			113			521
Development revenues		1,585			1,699			1,879			1,561
Operating expenses		(7,448	)		(8,464	)		(6,789	)		(5,670	)
Other expense, net		(242	)		(181	)		(587	)		(1,330	)
Net income (loss)	$	(5,339	)	$	(6,405	)	$	(5,384	)	$	(4,918	)
Beneficial conversion feature for convertible preferred stock		—			—			—			—
Net income (loss) allocable to common stock holders		(5,339	)		(6,405	)		(5,384	)		(4,918	)
Basic and diluted net loss per share	$	(0.41	)	$	(0.43	)	$	(0.26	)	$	(0.24	)