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Summary of Significant Accounting Policies - Additional Information (Details)
shares in Millions
 1 Months Ended 12 Months Ended
May 31, 2013
Dec. 31, 2017
USD ($)
Customer
Segment
shares
Dec. 31, 2016
USD ($)
Customer
Distributor
Segment
shares
Summary Of Significant Accounting Policies [Line Items]      
Cash equivalents investments with original maturities   $ 0 $ 0
Letters of credit issued in favour of landlord   500,000  
Impairment loss   0 0
Impairment of goodwill   0 0
Acquired technology intangible assets   9,400,000  
Useful life (in years) 11 years    
Amortization expense   1,240,000 584,000
2018   1,200,000  
2019   1,200,000  
2020   1,200,000  
2021   1,200,000  
2022   1,200,000  
Thereafter   900,000  
Accumulated amortization on intangible assets   $ 4,700,000 $ 3,400,000
Concentration risk percentage   100.00% 100.00%
Revenue recognized   $ 3,722,000 $ 6,724,000
Qualifying expenditures related to research   3,500,000 6,300,000
Interest or penalties related to income tax matters   $ 0 $ 0
Number of operating segment | Segment   1 1
Dilutive securities excluded from the calculations of diluted loss per share (in shares) | shares   20.5 4.2
Outstanding Warrants [Member]      
Summary Of Significant Accounting Policies [Line Items]      
Dilutive securities excluded from the calculations of diluted loss per share (in shares) | shares   19.5  
Options and Restricted Stock [Member]      
Summary Of Significant Accounting Policies [Line Items]      
Dilutive securities excluded from the calculations of diluted loss per share (in shares) | shares   1.0  
BARDA Contract [Member]      
Summary Of Significant Accounting Policies [Line Items]      
Revenue recognized   $ 3,700,000 $ 6,700,000
Customer Concentration Risk | Revenue Recognized [Member]      
Summary Of Significant Accounting Policies [Line Items]      
Number of customers | Customer   5 3
Concentration risk percentage   68.00% 65.00%
Number of distributor | Distributor     2
Customer Concentration Risk | Accounts Receivable [Member]      
Summary Of Significant Accounting Policies [Line Items]      
Number of customers | Customer   1 2
Concentration risk percentage   77.00% 57.00%
Minimum [Member]      
Summary Of Significant Accounting Policies [Line Items]      
Useful lives of the assets   3 years  
Maximum [Member]      
Summary Of Significant Accounting Policies [Line Items]      
Useful lives of the assets   5 years  
Letter of Credit [Member]      
Summary Of Significant Accounting Policies [Line Items]      
Letters of credit amount pursuant to lease agreement   $ 200,000